Department of Trauma and Orthopaedics, University Hospital of North Staffordshire, Stoke on Trent, Staffordshire, United Kingdom.
J Trauma Acute Care Surg. 2012 May;72(5):1375-9. doi: 10.1097/TA.0b013e318245267c.
Proximal femoral fracture is the most common reason for emergency orthopedic admission in the United Kingdom with an annual cost of £ 1.7 billion to the National Health Service. Surgical site infection (SSI) after proximal femoral fracture increases patient morbidity and mortality. Methicillin-resistant Staphylococcus aureus (MRSA) poses a particular risk in this patient cohort as a large proportion of these patients are residents of long-term care facilities and are therefore transient or chronic carriers of MRSA. We recorded the effect of three stages of care bundle development on the infection and specifically the MRSA rate after hemiarthroplasty over an 8-year period.
Data were collated retrospectively from the surgical site infection surveillance service. These data were prospectively collected and independently collated. The data were analyzed using the χ(2) test and the normal test for differences between two proportions.
Between October 2001 and June 2009, 1,830 hemiarthroplasties were performed. A statistically significant difference (p < 0.05) in SSI and MRSA rate was identified. The most effective care bundle included double skin preparation using alcoholic chlorhexidine, a single dose of intravenous co-amoxiclav (1.2 g) and gentamicin (240 mg) at induction, and implanted gentamicin-impregnated equine collagen at wound closure.
Adoption of our care bundle approach led to a reduction in SSI rate after hemiarthroplasty. The care bundle we propose is tailored to reduce MRSA infection and minimize risks associated with antibiotic prophylaxis. It is a simple and cost-effective improvement in the clinical care of this vulnerable group.
IV, therapeutic study.
英国最常见的紧急骨科入院原因是股骨近端骨折,国民保健服务系统每年为此花费 17 亿英镑。股骨近端骨折后手术部位感染(SSI)会增加患者的发病率和死亡率。耐甲氧西林金黄色葡萄球菌(MRSA)在这一患者群体中构成了特别的风险,因为这些患者中有很大一部分是长期护理机构的居民,因此是 MRSA 的临时或慢性携带者。我们记录了护理包开发的三个阶段对感染的影响,特别是在 8 年期间半髋关节置换术后的 MRSA 发生率。
数据从手术部位感染监测服务中回顾性收集。这些数据是前瞻性收集和独立整理的。使用卡方检验和两个比例差异的正态检验对数据进行分析。
2001 年 10 月至 2009 年 6 月期间,共进行了 1830 例半髋关节置换术。SSI 和 MRSA 发生率有统计学显著差异(p < 0.05)。最有效的护理包包括使用酒精氯己定进行双皮肤准备、诱导时单次静脉注射复方阿莫西林(1.2 g)和庆大霉素(240 mg)以及在伤口关闭时植入庆大霉素浸渍的马胶原。
采用我们的护理包方法可降低半髋关节置换术后 SSI 发生率。我们提出的护理包旨在降低 MRSA 感染风险,并最大限度地降低与抗生素预防相关的风险。这是对这一脆弱群体的临床护理的简单且具有成本效益的改进。
IV,治疗研究。