微生物组、疾病与恢复健康：一个亚稳态旅程。
Microbiota, disease, and back to health: a metastable journey.
机构信息
Gastroenterology Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.
出版信息
Sci Transl Med. 2012 Jun 6;4(137):137rv7. doi: 10.1126/scitranslmed.3004184.
Abstract
Alterations in the composition of the commensal microbiota have been observed in many complex diseases. Understanding the basis for these changes, how they relate to disease risk or activity, and the mechanisms by which the symbiotic state of colonization resistance and host homeostasis is restored is critical for future therapies aimed at manipulating the microbiota.
摘要
在许多复杂疾病中，观察到共生微生物群落的组成发生了改变。了解这些变化的基础、它们与疾病风险或活动的关系，以及恢复定植抵抗力和宿主内稳态共生状态的机制，对于旨在操纵微生物群的未来治疗方法至关重要。
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