Rhee Mun Su, Moritz Brélan E, Xie Gary, Glavina Del Rio T, Dalin E, Tice H, Bruce D, Goodwin L, Chertkov O, Brettin T, Han C, Detter C, Pitluck S, Land Miriam L, Patel Milind, Ou Mark, Harbrucker Roberta, Ingram Lonnie O, Shanmugam K T
Stand Genomic Sci. 2011 Dec 31;5(3):331-40. doi: 10.4056/sigs.2365342. Epub 2011 Dec 22.
Bacillus coagulans is a ubiquitous soil bacterium that grows at 50-55 °C and pH 5.0 and ferments various sugars that constitute plant biomass to L (+)-lactic acid. The ability of this sporogenic lactic acid bacterium to grow at 50-55 °C and pH 5.0 makes this organism an attractive microbial biocatalyst for production of optically pure lactic acid at industrial scale not only from glucose derived from cellulose but also from xylose, a major constituent of hemicellulose. This bacterium is also considered as a potential probiotic. Complete genome sequence of a representative strain, B. coagulans strain 36D1, is presented and discussed.
凝结芽孢杆菌是一种广泛存在于土壤中的细菌，能在50-55°C和pH 5.0的条件下生长，并将构成植物生物质的各种糖类发酵成L(+)-乳酸。这种产芽孢乳酸菌在50-55°C和pH 5.0条件下生长的能力，使其成为一种有吸引力的微生物生物催化剂，不仅可用于从纤维素衍生的葡萄糖，还可从半纤维素的主要成分木糖大规模工业生产光学纯乳酸。这种细菌也被认为是一种潜在的益生菌。本文展示并讨论了代表性菌株凝结芽孢杆菌36D1的完整基因组序列。
