Gazi University Faculty of Medicine, Department of Medical Microbiology, Ankara, 06500 Turkey;
IMA Fungus. 2011 Jun;2(1):29-32. doi: 10.5598/imafungus.2011.02.01.05. Epub 2011 May 13.
This contribution is based on the four presentations made at the Special Interest Group (SIG) meeting titled Gene Expression in Fungi held during IMC9 in Edinburgh. This overview is independent from other articles published or that will be published by each speaker. In the SIG meeting, basic principles of in vivo animal models for virulence studies were discussed. Infection associated genes of Candida albicans and fungal adaptation to the host was summarized. Azole susceptibility was evaluated as a combined result of several changes in expression of pertinent genes. Gene transfer in fungi, resulting in fungal evolution and gene adaptation to environmental factors, was reported.
本内容基于在爱丁堡举行的第 9 届国际分子真菌会议(IMC9)的真菌基因表达专题小组(SIG)会议上的四个专题报告。该综述与每位演讲者发表或即将发表的其他文章无关。在 SIG 会议上,讨论了用于毒力研究的体内动物模型的基本原则。总结了白色念珠菌感染相关基因和真菌对宿主的适应性。唑类药物敏感性被评估为相关基因表达的几种变化的综合结果。报道了真菌中的基因转移,导致真菌进化和基因适应环境因素。