Shah Jinesh M, Sundar Gangadhara, Tan Kong Bing, Zee Ying Kiat
Department of Ophthalmology, National University of Singapore, Singapore.
Orbit. 2012 Dec;31(6):425-7. doi: 10.3109/01676830.2012.689084. Epub 2012 Jun 8.
Merkel cell carcinoma of the eyelid is a rare tumor with less than 100 reported cases worldwide. We describe an unusual presentation of Merkel cell carcinoma of the eyelid in a 60 year old Asian male. He presented with multiple left lower lid conjunctival nodules, intense conjunctival erythema, as well as ipsilateral cervical lymphadenopathy. An incisional biopsy diagnosed him with Merkel cell carcinoma with a PET scan showing distant metastatic disease. He was then treated with chemotherapy. The combination of a presentation of conjunctival nodules and erythema, location in the lower eyelid and the conjunctiva, the presence of metastatic disease on diagnosis as well as an unusual immunohistochemical profile make this an unusual case.
眼睑默克尔细胞癌是一种罕见肿瘤，全球报告病例不足100例。我们描述了一名60岁亚洲男性眼睑默克尔细胞癌的不寻常表现。他表现为左眼下睑结膜多发结节、结膜强烈红斑以及同侧颈部淋巴结病。切开活检诊断他为默克尔细胞癌，正电子发射断层扫描显示有远处转移疾病。随后他接受了化疗。结膜结节和红斑表现、位于下睑和结膜、诊断时存在转移疾病以及不寻常的免疫组化特征相结合，使得这成为一个不寻常的病例。
