Department of Clinical Psychological Science, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Compr Psychiatry. 2012 Nov;53(8):1187-93. doi: 10.1016/j.comppsych.2012.04.008. Epub 2012 Jun 6.
Research looking at specific memory aberrations in the schizophrenia has primarily focused on their phenomenology using standardized semantic laboratory tasks. However, no study has investigated to what extent such aberrations have consequences for everyday episodic memories using more realistic false memory paradigms. Using a false memory paradigm where participants are presented with misleading suggestive information (Gudjonsson Suggestibility Scale), we investigated the susceptibility of patients with schizophrenia (n = 21) and healthy controls (n = 18) to post hoc misleading information acceptance and compliance. Patients with schizophrenia exhibited an increased susceptibility to go along with misleading suggestive items. Furthermore, they showed an increased tendency to change answers under conditions of social pressure. Underscoring previous findings on memory aberrations in schizophrenia, patients with schizophrenia had reduced levels of correct recognition (ie, true memory) relative to healthy controls. The effects remained stable when controlling for specific mediating variables such as symptom severity and intelligence in patients with schizophrenia. These findings are a first indication that social pressure and misleading information may impair source memory for everyday episodic memories in schizophrenia, and such impairment has clear consequences for treatment issues and forensic practice.
研究主要关注精神分裂症患者特定记忆异常的现象学，使用标准化的语义实验室任务。然而，没有研究调查这种异常在使用更现实的错误记忆范式时对日常情景记忆的影响程度。我们使用错误记忆范式，其中参与者接受误导性暗示信息（古德琼森暗示性量表），研究精神分裂症患者（n=21）和健康对照组（n=18）对事后误导性信息接受和顺从的易感性。精神分裂症患者表现出对误导性暗示项目的易感性增加。此外，他们在社会压力下表现出增加的改变答案的倾向。强调精神分裂症记忆异常的先前发现，与健康对照组相比，精神分裂症患者的正确识别率（即真实记忆）降低。在控制精神分裂症患者的特定中介变量（如症状严重程度和智力）后，这些影响仍然稳定。这些发现首次表明，社会压力和误导性信息可能会损害精神分裂症患者的日常情景记忆的来源记忆，这种损害对治疗问题和法医学实践有明显的影响。
