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阻塞性睡眠呼吸暂停低通气综合征患者的抑郁症状。

Depressive symptoms in patients with obstructive sleep apnea/hypopnea syndrome.

机构信息

Universidad Peruana Cayetano Heredia (UPCH), Lima, Peru.

出版信息

Sleep Breath. 2013 May;17(2):615-20. doi: 10.1007/s11325-012-0731-1. Epub 2012 Jun 9.

Abstract

OBJECTIVE

The objective of this study was to determine the frequency of depressive symptoms in Peruvian patients with obstructive sleep apnea/hypopnea (OSAH) and the association between the presence of depressive symptoms and OSAH severity.

METHODS

Physical examination, Beck Depression Inventory (BDI), and Epworth Sleepiness Scale (ESS) were applied, and a polysomnography test was performed.

RESULTS

Data on 312 patients, 12 % females, 46.1 ± 11.7 years of age, were analyzed. BDI and ESS scores were 8.3 ± 5.7 and 9.8 ± 5.5, respectively. A total of 244 (78 %) patients had OSAH: 27 % of the cases were mild, 23 % were moderate, and 50 % were severe. Eighteen percent of the population had depression. A univariate analysis found a relationship between depressive symptoms and OSAH, as well as with some polysomnographic variables related to OSAH severity. The association between depression and OSAH was not significant in the multivariate analysis.

CONCLUSIONS

No association was found between depressive symptoms and OSAH.

摘要

目的

本研究旨在确定秘鲁阻塞性睡眠呼吸暂停低通气(OSAH)患者出现抑郁症状的频率,以及抑郁症状与 OSAH 严重程度之间的关联。

方法

进行了体格检查、贝克抑郁量表(BDI)和爱泼沃斯嗜睡量表(ESS)评估,并进行了多导睡眠图检查。

结果

分析了 312 名患者的数据,其中女性占 12%,年龄为 46.1±11.7 岁。BDI 和 ESS 评分分别为 8.3±5.7 和 9.8±5.5。共有 244 名(78%)患者患有 OSAH:27%为轻度,23%为中度,50%为重度。18%的人群患有抑郁症。单因素分析发现抑郁症状与 OSAH 以及与 OSAH 严重程度相关的一些睡眠图变量之间存在关联。多变量分析未发现抑郁与 OSAH 之间存在关联。

结论

未发现抑郁症状与 OSAH 之间存在关联。

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