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以颈部窦道流脓及纵隔肿块为表现的霍奇金淋巴瘤。

Hodgkin's disease presenting as discharging neck sinuses and a mediastinal mass.

作者信息

Zolotar Meira, Olaleye Oladejo, Sherif Ali, Howe Rachael, Mathews John

机构信息

Department of Otolaryngology, Head & Neck Surgery, Russells Hall Hospital, West Midlands, UK.

出版信息

BMJ Case Rep. 2011 Jul 28;2011:bcr1220103669. doi: 10.1136/bcr.12.2010.3669.

Abstract

A 23-year-old Asian lady presented with a hard indurated midline neck swelling of 2 months duration without any upper aerodigestive tract or systemic symptoms of note. Her inflammatory markers were elevated and she was commenced on antibiotics. Ultrasound scan and fine needle aspiration cytology (FNAC) were inconclusive. A CT scan showed an ill-defined soft tissue mass anterior to and not well demarcated from the thyroid, and contiguous with a superior and anterior mediastinal mass. Incisional biopsy revealed necrosis and pockets of purulent material. Microbiology suggested a chronic pyogenic abscess negative for acid fast bacilli. She was treated with antituberculous therapy without resolution. She developed a discharging lateral neck mass with progressive increase of the mediastinal mass. She subsequently required a neck exploration and mediastinoscopy. Repeat mediastinal biopsies confirmed the diagnosis of Hodgkin's disease and no organisms on culture. She was commenced on chemotherapeutic treatment with a satisfactory outcome.

摘要

一名23岁的亚洲女性,颈部中线出现质地坚硬的硬结性肿物,持续2个月,无上呼吸道或消化道症状及其他明显的全身症状。她的炎症指标升高,开始使用抗生素治疗。超声扫描和细针穿刺细胞学检查(FNAC)结果不明确。CT扫描显示甲状腺前方有一个边界不清的软组织肿块,与甲状腺分界不清,并与上纵隔和前纵隔肿块相连。切开活检显示有坏死和脓性物质聚集。微生物学检查提示为慢性化脓性脓肿,抗酸杆菌阴性。她接受了抗结核治疗,但病情没有缓解。她出现了颈部外侧肿物破溃,并伴有纵隔肿物逐渐增大。随后她需要进行颈部探查和纵隔镜检查。再次进行纵隔活检确诊为霍奇金病,培养未发现病原体。她开始接受化疗,治疗效果满意。

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