Institut de Recherche pour le Développement, University of Montpellier, 34394 Montpellier, France.
Int J Parasitol. 2012 Jul;42(8):709-13. doi: 10.1016/j.ijpara.2012.05.004. Epub 2012 Jun 9.
Western gorillas (Gorilla gorilla) have been identified as the natural reservoir of the parasites that were the immediate precursor of Plasmodium falciparum infecting humans. Recently, a P. falciparum-like sequence was reported in a sample from a captive greater spot-nosed monkey (Cercopithecus nictitans), and was taken to indicate that this species may also be a natural reservoir for P. falciparum-related parasites. To test this hypothesis we screened blood samples from 292 wild C. nictitans monkeys that had been hunted for bushmeat in Cameroon. We detected Hepatocystis spp. in 49% of the samples, as well as one sequence from a clade of Plasmodium spp. previously found in birds, lizards and bats. However, none of the 292 wild C. nictitans harbored P. falciparum-like parasites.
西部大猩猩（Gorilla gorilla）已被确定为寄生虫的天然宿主，而这些寄生虫正是导致人类感染疟原虫（Plasmodium falciparum）的直接前体。最近，在一份来自圈养斑点鼻猴（Cercopithecus nictitans）的样本中报告了一种类似疟原虫（Plasmodium falciparum）的序列，并被认为该物种也可能是与疟原虫相关的寄生虫的天然宿主。为了验证这一假设，我们对在喀麦隆狩猎野味而采集的 292 只野生斑点鼻猴的血液样本进行了筛查。我们在 49%的样本中检测到了 Hepatocystis spp.，以及一个来自先前在鸟类、蜥蜴和蝙蝠中发现的疟原虫（Plasmodium spp.）分支的序列。然而，在 292 只野生斑点鼻猴中，没有任何一种携带类似疟原虫（Plasmodium falciparum）的寄生虫。
