Madlena Melinda, Banoczy Jolan, Gotz Gergely, Marton Sandor, Kaan Miklos, Nagy Gabor
Department of Paedodontics and Orthodontics, Semmelweis University, Budapest, Hungary.
Oral Health Dent Manag. 2012 Jun;11(2):57-61.
The aim of this pilot study was to evaluate the effects of different use of amine and stannous fluoride (AmF/SnF2)- containing toothpaste with and without a mouthrinse (Meridol®) on plaque accumulation and gingival health after four weeks' use in patients wearing fixed orthodontic appliances.
Plaque accumulation and periodontal variables were recorded in 40 volunteers (mean age: 20.1±5.6 years), who were randomly divided into two groups. They refrained from oral hygiene two days before each assessment. The test group brushed with AmF/SnF2 toothpaste twice daily for three minutes and rinsed with an AmF/SnF2 mouthrinse for 30 seconds. The control group used only the AmF/SnF2 toothpaste twice daily, toothbrushing for three minutes.
Baseline values for plaque index (PI) and gingival index (GI) were 2.21±0.52 and 1.98±0.58 (mean±SD) in the test group, 2.29±0.42 and 2.02±0.44 in the control group. After four weeks, PI and GI were 1.32±0.42 and 0.93±0.59 in the test group, and 1.27±0.52 and 1.09±0.51 in the control group, respectively. Bleeding on probing at baseline was 40% in the test group and 37.5% for the controls; at the final evaluation, these values were 10.1% and 12.7%, respectively. All of the indices were reduced significantly in both groups. There was no statistically significant difference between the groups (P<0.05).
Based on the findings of this pilot study, it is suggested that the use of AmF/SnF2-containing products resulted in beneficial clinical effects on plaque accumulation and gingival health after placement of fixed orthodontic appliances. These beneficial effects may be more pronounced after long-term and combined use of these products. A six-month duration study with a larger sample of participants is needed to confirm the promising results from this pilot.
本初步研究旨在评估含胺和氟化亚锡（AmF/SnF₂）的牙膏在使用和不使用漱口水（Meridol®）的情况下，对佩戴固定正畸矫治器的患者使用四周后牙菌斑堆积和牙龈健康的影响。
记录40名志愿者（平均年龄：20.1±5.6岁）的牙菌斑堆积情况和牙周变量，这些志愿者被随机分为两组。每次评估前两天，他们停止口腔卫生护理。试验组每天使用含AmF/SnF₂的牙膏刷牙两次，每次三分钟，并用含AmF/SnF₂的漱口水漱口30秒。对照组仅每天使用含AmF/SnF₂的牙膏刷牙两次，每次三分钟。
试验组的菌斑指数（PI）和牙龈指数（GI）基线值分别为2.21±0.52和1.98±0.58（平均值±标准差），对照组分别为（平均值±标准差）2.29±0.42和2.02±0.44。四周后，试验组的PI和GI分别为1.32±0.42和0.93±0.59，对照组分别为1.27±0.52和1.09±0.51。基线时试验组探诊出血率为40%，对照组为37.5%；在最终评估时，这些值分别为10.1%和12.7%。两组所有指标均显著降低。两组之间无统计学显著差异（P<0.05）。
基于本初步研究的结果，建议使用含AmF/SnF₂的产品对固定正畸矫治器佩戴后的牙菌斑堆积和牙龈健康产生有益的临床效果。长期联合使用这些产品后，这些有益效果可能会更明显。需要进行一项为期六个月、样本量更大的研究来证实本初步研究的良好结果。
