Loeffler Christoph, Mols Georg, Hecksteden Kai, Pfeiffer Jens, Ridder Gerd J
Department of Otorhinolaryngology-Head and Neck Surgery, University of Freiburg, Freiburg, Germany.
BMJ Case Rep. 2011 Jun 29;2011:bcr0420114100. doi: 10.1136/bcr.04.2011.4100.
The authors report on a fatal case of severe tetanus in a 74-year old woman. Despite comprehensive intensive care management they could not achieve a satisfying control of the autonomic dysfunction caused by tetanus. By now there is no established therapy for the treatment of the autonomic dysfunction. This report demonstrates the dismal prognosis of severe tetanus in the older people, which is often complicated by cardiovascular comorbidity and underlines the importance of tetanus prevention by sufficient vaccination.
作者报告了一例74岁女性严重破伤风致死病例。尽管采取了全面的重症监护管理措施,但他们仍未能令人满意地控制破伤风引起的自主神经功能障碍。目前尚无治疗自主神经功能障碍的确立疗法。本报告显示了老年人严重破伤风的预后不佳,其常并发心血管合并症,并强调了通过充分接种疫苗预防破伤风的重要性。