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非血液系统实体瘤中的高尿酸血症性肾衰竭：一例病例报告及文献复习

Hyperuricemic renal failure in nonhematologic solid tumors: a case report and review of the literature.

作者信息

Saini Neeraj, Pyo Lee Kyeong, Jha Smita, Patel Sanket, Bonthu Neelima, Kansagra Ankit, Bhatia Ashmeet, Martinez Sandra E, Patel Jaymin, Altamimi Sarah, Ghotb Sara

机构信息

Department of Internal Medicine, North Shore Medical Centre (NSMC), Salem, MA 01970, USA.

出版信息

Case Rep Med. 2012;2012:314056. doi: 10.1155/2012/314056. Epub 2012 May 27.

DOI:10.1155/2012/314056
PMID:22693518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3368227/
Abstract

Tumor lysis syndrome (TLS) is an oncologic emergency that is caused by massive tumor cell lysis. It is commonly associated with hematological cancers like leukemia and lymphoma and uncommonly with solid nonhematologic tumors as well. However, spontaneous tumor lysis syndrome (STLS) without any cytotoxic chemotherapy rarely occurs in solid tumors. We describe a case of STLS in a metastatic adenocarcinoma of unknown primary and review the literature of STLS in solid non-hematologic tumors to identify various risk factors for pathogenesis of this entity.

摘要

肿瘤溶解综合征（TLS）是一种由大量肿瘤细胞溶解引起的肿瘤急症。它通常与白血病和淋巴瘤等血液系统癌症相关，也较少见于实体非血液系统肿瘤。然而，在实体肿瘤中，很少发生无任何细胞毒性化疗的自发性肿瘤溶解综合征（STLS）。我们报告一例原发灶不明的转移性腺癌患者发生STLS的病例，并回顾实体非血液系统肿瘤中STLS的文献，以确定该疾病发病机制的各种危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/495a/3368227/390d1ca4267a/CRIM2012-314056.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/495a/3368227/390d1ca4267a/CRIM2012-314056.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/495a/3368227/390d1ca4267a/CRIM2012-314056.001.jpg

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Severe spontaneous acute tumor lysis syndrome and hypoglycemia in patient with germ cell tumor.生殖细胞肿瘤患者出现严重自发性急性肿瘤溶解综合征和低血糖症。
Tumori. 2010 Nov-Dec;96(6):1040-3.
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Maxillary Sinus Squamous Cell Carcinoma Presenting with Fatal Tumor Lysis Syndrome: A Case Report and Review of the Literature.
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