Han Zhi, Luo Jun, Kong Ling-Yi
State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
J Asian Nat Prod Res. 2012;14(8):743-7. doi: 10.1080/10286020.2012.688956. Epub 2012 Jun 14.
Two new tocopherol polymers, chroman-type dimer named ferotocodimer A (1) and spiro-type trimer named ferotocotrimer E (2), were isolated from the seeds of Euryale ferox. Their structures were elucidated on the basis of spectroscopic methods including HR-ESI-MS and 1D and 2D NMR. The absolute configurations of 1 and 2 were determined by CD and ROESY experiments.
从芡实种子中分离出两种新的生育酚聚合物，一种是名为ferotocodimer A（1）的苯并二氢吡喃型二聚体，另一种是名为ferotocotrimer E（2）的螺型三聚体。基于包括高分辨电喷雾电离质谱（HR-ESI-MS）以及一维和二维核磁共振（1D和2D NMR）在内的光谱方法阐明了它们的结构。通过圆二色光谱（CD）和旋转坐标系中的核Overhauser效应光谱（ROESY）实验确定了1和2的绝对构型。
