State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Science, Chinese Academy of Sciences, Beijing 100085, China.
Chemosphere. 2012 Nov;89(11):1307-15. doi: 10.1016/j.chemosphere.2012.05.079. Epub 2012 Jun 12.
This study investigated the presence and distribution of 22 antibiotics, including eight quinolones, nine sulfonamides and five macrolides, in the water, sediments, and biota samples from Baiyangdian Lake, China. A total of 132 samples were collected in 2008 and 2010, and laboratory analyses revealed that antibiotics were widely distributed in the lake. Sulfonamides were the dominant antibiotics in the water (0.86-1563 ng L(-1)), while quinolones were prominent in sediments (65.5-1166 μg kg(-1)) and aquatic plants (8.37-6532 μg kg(-1)). Quinolones (17.8-167 μg kg(-1)) and macrolides [from below detection limit (BDL) to 182 μg kg(-1)] were often found in aquatic animals and birds. Salvinia natans exhibited the highest bioaccumulation capability for quinolones among three species of aquatic plants. Geographical differences of antibiotic concentrations were greatly due to anthropogenic activities. Sewage discharged from Baoding City was likely the main source of antibiotics in the lake. Risk assessment of antibiotics on aquatic organisms suggested that algae and aquatic plants might be at risk in surface water, while animals were likely not at risk.
本研究调查了中国白洋淀水中、沉积物中和生物样本中 22 种抗生素（包括 8 种喹诺酮类、9 种磺胺类和 5 种大环内酯类）的存在和分布情况。2008 年和 2010 年共采集了 132 个样本，实验室分析表明抗生素在湖中广泛分布。磺胺类抗生素在水中（0.86-1563ng/L）占主导地位，而喹诺酮类抗生素在沉积物（65.5-1166μg/kg）和水生植物（8.37-6532μg/kg）中含量较高。在水生动物和鸟类中，通常可以检测到喹诺酮类（17.8-167μg/kg）和大环内酯类抗生素[低于检测限（BDL）至 182μg/kg]。三种水生植物中，水葫芦对喹诺酮类抗生素的生物积累能力最强。抗生素浓度的地理差异主要归因于人为活动。保定市排放的污水可能是湖中抗生素的主要来源。对抗生素对水生生物的风险评估表明，地表水的藻类和水生植物可能面临风险，而动物则不太可能面临风险。
