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有效使用酒精安慰剂的一些边界条件。

Some boundary conditions for effective use of alcohol placebos.

作者信息

Martin C S, Earleywine M, Finn P R, Young R D

机构信息

Department of Psychology, Indiana University, Bloomington 47405.

出版信息

J Stud Alcohol. 1990 Nov;51(6):500-5. doi: 10.15288/jsa.1990.51.500.

DOI:10.15288/jsa.1990.51.500
PMID:2270058
Abstract

The present research assessed the conditions under which subjects who consume alcohol and those who consume a placebo beverage, and who report consuming alcohol on a manipulation check question, are equivalent with respect to subjective responses to alcohol. Male subjects were told that they were drinking alcohol and consumed one of four beverages: alcoholic beer, nonalcoholic beer, vodka and tonic with lime, or tonic with lime. Measures of subjective intoxication, body sensations and breath alcohol were taken at different times during and after beverage consumption. Subjective intoxication ratings were higher for subjects who received alcohol, compared to subjects who received a placebo and reported consuming alcohol, when alcohol subjects achieved blood alcohol concentrations at and above .04%. These two groups did not differ in subjective intoxication ratings when alcohol subjects achieved blood alcohol concentrations below .04%. These data suggest that the orthogonal manipulation of alcohol consumption and expectancy effects is problematic at and above blood alcohol concentrations of .04%.

摘要

本研究评估了饮酒者和饮用安慰剂饮料者在接受酒精消费操纵检查问题时报告饮酒的情况下,对酒精主观反应相当的条件。男性受试者被告知他们正在饮酒,并饮用了四种饮料之一:酒精啤酒、无酒精啤酒、加酸橙的伏特加汤力水或加酸橙的汤力水。在饮料饮用期间和之后的不同时间测量了主观醉酒程度、身体感觉和呼气酒精含量。当饮酒受试者的血液酒精浓度达到或高于0.04%时,与接受安慰剂并报告饮酒的受试者相比,接受酒精的受试者的主观醉酒评分更高。当饮酒受试者的血液酒精浓度低于0.04%时,这两组在主观醉酒评分上没有差异。这些数据表明,在血液酒精浓度达到0.04%及以上时,酒精消费和预期效应的正交操纵存在问题。

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