O'Malley S S, Maisto S A
Addict Behav. 1984;9(2):111-20. doi: 10.1016/0306-4603(84)90049-2.
The present experiment was designed to investigate whether changes in internal sensations and affect are used to discriminate intoxication and to determine how the discriminability of these cues is affected by dose, acquired tolerance, and the setting in which alcohol is consumed. Setting varied according to whether subjects were distracted or not distracted from attending to alcohol induced changes. Furthermore, subjects drank either a placebo beverage or one of two doses of alcohol. The results showed an interaction between dose and setting, which suggested that subjects who participated in a distracting task were less accurate in the evaluation of their intoxication and were more easily misled into believing that they had consumed alcohol when they had actually received a placebo. Additional measures suggested that the distracted subjects did not base their intoxication ratings as closely on changes associated with alcohol consumption. Acquired tolerance to alcohol also affected the perception of intoxication and influenced the discriminability of changes in internal sensations and affect. The findings on tolerance are related to motives for increasing alcohol consumption over time and to the inefficacy of blood alcohol level discrimination training with alcoholics.
本实验旨在研究内部感觉和情感的变化是否被用于辨别醉酒状态,以及确定这些线索的可辨别性如何受到剂量、习得性耐受性以及饮酒环境的影响。环境根据受试者是否被分散注意力而无法关注酒精引起的变化而有所不同。此外,受试者饮用的要么是安慰剂饮料,要么是两种剂量酒精中的一种。结果显示剂量和环境之间存在相互作用,这表明参与分心任务的受试者在评估自己的醉酒状态时准确性较低,并且更容易被误导,误以为自己饮用了酒精,而实际上他们服用的是安慰剂。其他测量结果表明,分心的受试者在评定醉酒程度时,与饮酒相关变化的关联程度较低。对酒精的习得性耐受性也会影响对醉酒的感知,并影响内部感觉和情感变化的可辨别性。关于耐受性的研究结果与随着时间推移增加酒精摄入量的动机以及对酗酒者进行血液酒精水平辨别训练的无效性有关。