日常皮肤护理习惯与癌症患者皮肤疹和症状风险。

Daily skin care habits and the risk of skin eruptions and symptoms in cancer patients.

机构信息

Skin Cancer/Chemotherapy Skin Care Center, Seoul National University Cancer Hospital, Seoul; Department of Dermatology, Seoul, National University College of Medicine, Seoul; Institute of Dermatological Science, Medical Research Center, Seoul National University, Seoul.

Gastric Cancer Center, Seoul National University Cancer Hospital, Seoul; Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul.

出版信息

Ann Oncol. 2012 Aug;23(8):1992-1998. doi: 10.1093/annonc/mds141. Epub 2012 Jun 13.

DOI:10.1093/annonc/mds141

PMID:22700992

Abstract

BACKGROUND

Cancer patients are at high risk for skin problems because rapidly proliferating skin cells are susceptible to anticancer therapies. However, the effects of daily skin care habits on development of skin problems in cancer patients have rarely been studied.

PATIENTS AND METHODS

We conducted a survey of daily skin care habits and the presence of skin problems in 866 cancer patients.

RESULTS

Hot water bath>1 h significantly increased the risk of definite eruptions [odds ratio (OR) 4.09] and the risk of itching or pain on the skin (OR 1.73). Diligent use of moisturizers did not decrease the risk of definite eruptions and symptoms, and daily bathing, scrubbing off the skin while bathing, and sun protection did not influence the risk of definite eruptions and symptoms. Subgroup analysis of 183 breast cancer patients showed results similar to the total results, including that hot water bath>1 h significantly increased the risk of definite eruptions (OR 3.41).

CONCLUSIONS

Being a cross-sectional study, our study could not prove causality. However, at the present stage of knowledge, avoidance of hot water baths of protracted duration should be first emphasized in patient education to prevent skin problems in cancer patients.

摘要

背景

由于快速增殖的皮肤细胞容易受到抗癌疗法的影响，癌症患者面临着皮肤问题的高风险。然而，日常皮肤护理习惯对癌症患者皮肤问题发展的影响很少被研究。

患者和方法

我们对 866 名癌症患者的日常皮肤护理习惯和皮肤问题的存在情况进行了调查。

结果

热水浴>1 小时显著增加了明确皮疹的风险（比值比 [OR] 4.09）和皮肤瘙痒或疼痛的风险（OR 1.73）。勤用保湿剂并不能降低明确皮疹和症状的风险，每天洗澡、洗澡时搓擦皮肤以及防晒并不影响明确皮疹和症状的风险。对 183 名乳腺癌患者的亚组分析结果与总结果相似，包括热水浴>1 小时显著增加了明确皮疹的风险（OR 3.41）。