Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Indian J Pharmacol. 2012 May;44(3):319-25. doi: 10.4103/0253-7613.96302.
Although almost all psychotropic medications available worldwide are readily available in India, there is meager data in this country on the prescription patterns of psychiatrists.
To study the first prescription handed over to patients attending the psychiatry outpatient clinic of a tertiary care hospital.
Data of all patients (for the period of January 1, 2009 to November 30, 2010; diagnosed with an ICD-10 diagnosis of F2-F4) were extracted from the computer-based registry and analyzed.
Ten thousand two hundred and fourteen (10 214) patients were diagnosed to have a diagnosis of F2-F4 ICD-10 category. In all diagnostic groups, olanzapine was the most commonly prescribed antipsychotic followed by risperidone. Very few patients (8%) received typical antipsychotic medication. In all diagnostic groups, escitalopram was the most commonly prescribed antidepressant; other frequently prescribed antidepressants were sertraline, paroxetine, and venlafaxine. Among the mood stabilizers, valproate was preferred over lithium. In all the groups, more than half of the patients were prescribed benzodiazepines, clonazepam being the most commonly prescribed agent, followed by lorazepam. The mean number of psychotropic medications was highest in the bipolar disorder group. Very few patients received the combination of same group of drugs.
Olanzapine, escitalopram, and clonazepam are the most commonly prescribed antipsychotic, antidepressants, and benzodiazepines, respectively. Valproate was preferred over lithium as a mood stabilizer. In general, the prescription trends were in accordance to the recommendations of various treatment guidelines, except for the use of benzodiazepines, which was higher.
尽管全球几乎所有的精神药物在印度都能轻易获得,但这个国家在精神科医生的处方模式方面的数据却很少。
研究在一家三级护理医院的精神科门诊就诊的患者首次拿到的处方。
从基于计算机的登记处提取了 2009 年 1 月 1 日至 2010 年 11 月 30 日期间所有(被诊断为 ICD-10 F2-F4 诊断类别的)患者的数据,并进行了分析。
10214 名患者被诊断为患有 F2-F4 ICD-10 类别。在所有诊断组中,奥氮平是最常开的抗精神病药物,其次是利培酮。极少数患者(8%)接受了典型的抗精神病药物治疗。在所有诊断组中,艾司西酞普兰是最常开的抗抑郁药;其他经常开的抗抑郁药是舍曲林、帕罗西汀和文拉法辛。在心境稳定剂中,丙戊酸盐优先于锂盐。在所有组中,超过一半的患者开了苯二氮䓬类药物,其中氯硝西泮是最常开的药物,其次是劳拉西泮。在双相障碍组中,精神药物的平均数量最高。很少有患者同时接受同一组药物的联合治疗。
奥氮平、艾司西酞普兰和氯硝西泮分别是最常开的抗精神病药、抗抑郁药和苯二氮䓬类药物。丙戊酸盐优先于锂盐作为心境稳定剂。一般来说,处方趋势符合各种治疗指南的建议,除了苯二氮䓬类药物的使用较高外。