Rare Metals Research Center, Korea Institute of Geoscience and Mineral Resources, Daejeon 305-350, Korea.
Biosens Bioelectron. 2012 Oct-Dec;38(1):184-8. doi: 10.1016/j.bios.2012.05.033. Epub 2012 Jun 6.
A novel glucose biosensor was developed based on the adsorption of glucose oxidase at a TiO(2)-Graphene (GR) nanocomposite electrode. A TiO(2)-GR composite was synthesized from a colloidal mixture of TiO(2) nanoparticles and graphene oxide (GO) nanosheets by an aerosol assisted self-assembly (AASA). The particle morphology of all TiO(2)-GR composites was spherical in shape. It was observed that micron-sized TiO(2) particles were encapsulated by GR nanosheets and that the degree of encapsulation was proportional to the ratio of GO/TiO(2). The amperometric response of the glucose biosensor fabricated by the TiO(2)-GR composite was linear against a concentration of glucose ranging from 0 to 8mM at -0.6 V. The highest sensitivity was noted at about 6.2 μA/mMcm(2). The as prepared glucose biosensor based on the TiO(2)-GR composite showed higher catalytic performance for glucose redox than a pure TiO(2) and GR biosensor.
基于纳米二氧化钛-石墨烯（GR）复合物修饰电极对葡萄糖氧化酶的吸附作用，研制出了一种新型葡萄糖生物传感器。采用气溶胶辅助自组装（AASA）法，由 TiO2 纳米粒子和氧化石墨烯（GO）纳米片的胶体混合物合成了 TiO2-GR 复合材料。所有 TiO2-GR 复合材料的颗粒形态均为球形。观察到微米级 TiO2 颗粒被 GR 纳米片包裹，并且包裹程度与 GO/TiO2 的比例成正比。由 TiO2-GR 复合材料制备的葡萄糖生物传感器在-0.6 V 时对葡萄糖浓度在 0 至 8mM 范围内的安培响应呈线性关系。在约 6.2 μA/mMcm2 时，灵敏度最高。与纯 TiO2 和 GR 生物传感器相比，基于 TiO2-GR 复合材料的葡萄糖生物传感器对葡萄糖氧化还原具有更高的催化性能。
