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[乙醛和乙醇作用下大鼠血清蛋白的组成]

[Composition of rat serum proteins under the effect of acetaldehyde and ethanol].

作者信息

Bozhko G Kh, Strelianaia O I, Voloshyn P V

出版信息

Ukr Biokhim Zh (1978). 1990 Sep-Oct;62(5):19-24.

PMID:2270618
Abstract

Concentration and composition of rat serum proteins have been studied both under the isolated acetaldehyde effect and against a background of the action of acute and chronic intoxication by ethanol. Acetaldehyde evoked an increase in the concentration of the total serum proteins, the value of this parameter remaining unchanged under the ethanol effect. A comparison of ethanol and acetaldehyde effects gives ground to suppose that the quantitative redistribution of blood serum proteins which observed under ethanol intoxication is to a considerable extent a result of the acetaldehyde effect and is determined by aggregation of proteins.

摘要

已经在单独的乙醛作用下以及在乙醇急性和慢性中毒作用的背景下研究了大鼠血清蛋白的浓度和组成。乙醛引起血清总蛋白浓度增加,在乙醇作用下该参数值保持不变。对乙醇和乙醛作用的比较使我们有理由推测,在乙醇中毒时观察到的血清蛋白定量重新分布在很大程度上是乙醛作用的结果,并且是由蛋白质聚集决定的。

相似文献

1
[Composition of rat serum proteins under the effect of acetaldehyde and ethanol].[乙醛和乙醇作用下大鼠血清蛋白的组成]
Ukr Biokhim Zh (1978). 1990 Sep-Oct;62(5):19-24.
2
[The acute and chronic action of ethanol on blood serum proteins in rats].[乙醇对大鼠血清蛋白的急性和慢性作用]
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[Changes in concentration of the blood serum malondialdehyde due to a one-time and long-term ethanol and acetaldehyde administration].[一次性及长期给予乙醇和乙醛后血清丙二醛浓度的变化]
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Ethanol and acetaldehyde do not increase the blood-brain and blood-retinal barrier permeability to sodium fluorescein.乙醇和乙醛不会增加血脑屏障和血视网膜屏障对荧光素钠的通透性。
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