Bozhko G Kh, Strelianaia O I, Voloshyn P V
Ukr Biokhim Zh (1978). 1990 Sep-Oct;62(5):19-24.
Concentration and composition of rat serum proteins have been studied both under the isolated acetaldehyde effect and against a background of the action of acute and chronic intoxication by ethanol. Acetaldehyde evoked an increase in the concentration of the total serum proteins, the value of this parameter remaining unchanged under the ethanol effect. A comparison of ethanol and acetaldehyde effects gives ground to suppose that the quantitative redistribution of blood serum proteins which observed under ethanol intoxication is to a considerable extent a result of the acetaldehyde effect and is determined by aggregation of proteins.
已经在单独的乙醛作用下以及在乙醇急性和慢性中毒作用的背景下研究了大鼠血清蛋白的浓度和组成。乙醛引起血清总蛋白浓度增加,在乙醇作用下该参数值保持不变。对乙醇和乙醛作用的比较使我们有理由推测,在乙醇中毒时观察到的血清蛋白定量重新分布在很大程度上是乙醛作用的结果,并且是由蛋白质聚集决定的。