Department of Plant Physiology and Plant Molecular Biology , University of Plovdiv , 24 Tsar Assen str., Plovdiv 4000 , Bulgaria.
AoB Plants. 2012;2012:pls014. doi: 10.1093/aobpla/pls014. Epub 2012 Jun 4.
Hydrogen peroxide (H(2)O(2)) was initially recognized as a toxic reactive oxygen species, able to cause damage to a variety of cellular structures. However, it became clear in the last decade that H(2)O(2) can also act as a potent signalling molecule, involved in a plethora of physiological functions.
In the present review, we offer a brief summary of H(2)O(2) signalling events and focus on the mechanisms of its perception and signal transduction, the factors that act downstream, as well as H(2)O(2) interference with other information transfer mechanisms.
The significant scientific effort in the last 10 years to determine the position of H(2)O(2) in signal transduction networks in plants demonstrated that it is essential for both the communication with external biotic and abiotic stimuli and the control of developmentally regulated processes. In addition, H(2)O(2) complements, synergizes or antagonizes many cellular regulatory circuits by active interaction with other signals and plant hormones during growth, development and stress responses. Therefore, further understanding of H(2)O(2) signal transduction is not only of fundamental, but also of practical importance, since this knowledge may contribute to improve agricultural practices and reduce stress-induced damage to crops.
过氧化氢（H₂O₂）最初被认为是一种有毒的活性氧物质，能够对多种细胞结构造成损伤。然而，在过去的十年中，人们清楚地认识到 H₂O₂ 也可以作为一种有效的信号分子，参与多种生理功能。
在本次综述中，我们简要总结了 H₂O₂ 信号事件，并重点介绍了其感知和信号转导的机制、下游作用的因素，以及 H₂O₂ 对其他信息传递机制的干扰。
过去十年中，科学界为确定 H₂O₂ 在植物信号转导网络中的位置做出了巨大努力，这表明 H₂O₂ 对于与外部生物和非生物刺激的通讯以及对发育调控过程的控制都是必不可少的。此外，H₂O₂ 通过与其他信号和植物激素的积极相互作用，在生长、发育和应激反应过程中补充、协同或拮抗许多细胞调节回路。因此，进一步了解 H₂O₂ 信号转导不仅具有基础性，而且具有实际重要性，因为这一知识可能有助于改善农业实践，并减少应激对作物造成的损害。
