Cardiovascular Research Group, University of Manchester, UK.
Ann Med. 2012 Jun;44 Suppl 1:S74-84. doi: 10.3109/07853890.2012.663928.
The advent of the obesity epidemic has highlighted the need to re-assess more closely the pathophysiology of obesity-related hypertension with the aim of identifying new therapies. In this article, we review the role of the renin-angiotensin-aldosterone system, sympathetic nervous system, and inflammation in relation to the pathophysiology of this condition. We also discuss the potential role of the perivascular adipose tissue in the context of obesity-related hypertension.
肥胖症的流行突显了需要更密切地重新评估与肥胖相关的高血压的病理生理学，目的是确定新的治疗方法。在本文中，我们回顾了肾素-血管紧张素-醛固酮系统、交感神经系统和炎症与该病症的病理生理学之间的关系。我们还讨论了血管周围脂肪组织在肥胖相关高血压中的潜在作用。
