Williamson A M, Teo R K, Sanderson J
Int Arch Occup Environ Health. 1982;50(3):273-86. doi: 10.1007/BF00378089.
Mercury is a known neurotoxin. Evidence from animal studies show behavioural impairment which can be long-lasting, after low-level exposure to mercury. Human research, however, has not been conclusive. Chronic, high-level mercury exposure such as occurred in Japan, and the Middle East, Causes long-lasting and profound neurological damage. However the effects of low-level exposure, such as occurs in occupational exposure, are far from clear. This study used a comprehensive test battery based on an information processing framework to compare a group of twelve chronically mercury-exposed workers with a matched control group. The mercury-exposed group showed poorer psychomotor co-ordination and premature fatigue, although simple motor responses were not affected. General arousal levels also remained unaffected but mercury-exposed workers were superior in sustaining attention. In spite of this, the mercury-exposed group showed clear deficits in short-term memory.
汞是一种已知的神经毒素。动物研究证据表明,低水平接触汞后会出现长期的行为损伤。然而,人体研究尚无定论。日本和中东地区发生的慢性、高水平汞接触会导致长期且严重的神经损伤。然而,职业接触等低水平接触的影响尚不清楚。本研究使用了一套基于信息处理框架的综合测试组,将一组12名长期接触汞的工人与一个匹配的对照组进行比较。接触汞的组表现出较差的心理运动协调能力和过早疲劳,尽管简单的运动反应未受影响。总体唤醒水平也未受影响,但接触汞的工人在持续注意力方面表现更优。尽管如此,接触汞的组在短期记忆方面仍存在明显缺陷。