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日本阿麻町乡村岛屿城镇的痴呆症和轻度认知障碍患病率。

Prevalence of Dementia and Mild Cognitive Impairment in the Rural Island Town of Ama-cho, Japan.

作者信息

Wada-Isoe Kenji, Uemura Yusuke, Nakashita Satoko, Yamawaki Mika, Tanaka Kenichiro, Yamamoto Mikie, Shimokata Hiroshi, Nakashima Kenji

机构信息

Division of Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Obu, Japan.

出版信息

Dement Geriatr Cogn Dis Extra. 2012 Jan;2(1):190-9. doi: 10.1159/000338244. Epub 2012 Apr 24.

Abstract

AIMS

In order to determine the prevalence of dementia and mild cognitive impairment (MCI), we conducted a population-based study in Japan.

METHODS

Participants included 924 subjects aged 65 years or older who resided in the town of Ama-cho. In phase 1 of the study, the Mini-Mental State Examination and Clinical Dementia Rating were administered for screening purposes. In phase 2 of the study, the subjects who screened positive were further examined by neurologists. Dementia and MCI were diagnosed by means of DSM-IV and International Working Group on MCI criteria, respectively.

RESULTS

By the prevalence date of June 1, 2010, 24 subjects had deceased or lived outside the town. In total, 723 of the remaining 900 subjects received a phase 1 test. In phase 2, 98 subjects were diagnosed with amnestic MCI, 113 subjects with non-amnestic MCI, and 82 subjects with dementia. Of the subjects who did not receive the phase 1 test, 66 subjects were diagnosed as having dementia according to data from their town medical card or the Long-term Care Insurance System. The crude prevalence of amnestic MCI, non-amnestic MCI, and dementia were 10.9, 12.6, and 16.4%, respectively.

CONCLUSION

Consistent with the striking increase in the number of elderly individuals, we report higher prevalence of MCI and dementia in Japan than previously described.

摘要

目的

为了确定痴呆症和轻度认知障碍(MCI)的患病率,我们在日本开展了一项基于人群的研究。

方法

参与者包括居住在阿万町的924名65岁及以上的受试者。在研究的第一阶段,使用简易精神状态检查表和临床痴呆评定量表进行筛查。在研究的第二阶段,对筛查呈阳性的受试者由神经科医生进行进一步检查。分别根据《精神疾病诊断与统计手册》第四版和国际MCI工作组标准诊断痴呆症和MCI。

结果

截至2010年6月1日患病率统计日期,有24名受试者已去世或不住在该镇。在其余900名受试者中,共有723人接受了第一阶段测试。在第二阶段,98名受试者被诊断为遗忘型MCI,113名受试者被诊断为非遗忘型MCI,82名受试者被诊断为痴呆症。在未接受第一阶段测试的受试者中,根据其城镇医疗卡或长期护理保险系统的数据,有66名受试者被诊断患有痴呆症。遗忘型MCI、非遗忘型MCI和痴呆症的粗患病率分别为10.9%、12.6%和16.4%。

结论

与老年人数的显著增加相一致,我们报告日本MCI和痴呆症的患病率高于先前描述的水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54d7/3379729/9ea83ce17ccf/dee-0002-0190-g01.jpg

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