National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Nature. 2012 Jun 20;486(7403):335-40. doi: 10.1038/nature11170.
Two studies of H5N1 avian influenza viruses that had been genetically engineered to render them transmissible between ferrets have proved highly controversial. Divergent opinions exist about the importance of these studies of influenza transmission and about potential 'dual use' research implications. No consensus has developed yet about how to balance these concerns. After not recommending immediate full publication of earlier, less complete versions of the studies, the United States National Science Advisory Board for Biosecurity subsequently recommended full publication of more complete manuscripts; however, controversy about this and similar research remains.
两项关于 H5N1 禽流感病毒的研究已经被证明极具争议性，这些研究通过基因工程使病毒能够在雪貂之间传播。人们对这些流感传播研究的重要性以及潜在的“双重用途”研究意义存在不同看法。对于如何平衡这些关注点，目前尚未达成共识。在没有建议立即全面公布之前那些不完整的、较早期版本的研究之后，美国生物安保国家科学咨询委员会随后建议全面公布更完整的手稿；然而，对于这一研究和类似研究的争议仍然存在。
