Patra P B, Sanyal S, Biswas N M
Andrologia. 1979 Jul-Aug;11(4):273-8. doi: 10.1111/j.1439-0272.1979.tb02204.x.
Nicotine caused a fall in primary spermatocyte number together with a retardation of spermatocyte to spermatid conversions process. These effects of nicotine were possibly secondary to increased activity of adrenomedullary catecholamines, since the antispermatogenic effect of nicotine was prevented by phentolamine, a known blocker of catecholamine action at the alpha-receptor level.
尼古丁导致初级精母细胞数量减少，同时精母细胞向精子细胞的转化过程延迟。尼古丁的这些作用可能继发于肾上腺髓质儿茶酚胺活性增加，因为尼古丁的抗生精作用可被酚妥拉明（一种已知的在α受体水平阻断儿茶酚胺作用的阻滞剂）所阻止。
