Department of Neurology, McGill University, Montreal General Hospital, Montreal, Québec, Canada.
Mov Disord. 2012 Jun;27(7):913-6. doi: 10.1002/mds.25037. Epub 2012 May 30.
Idiopathic rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia that is an important risk factor for Parkinson's disease (PD) and Lewy body dementia. Its prevalence is unknown. One barrier to determining prevalence is that current screening tools are too long for large-scale epidemiologic surveys. Therefore, we designed the REM Sleep Behavior Disorder Single-Question Screen (RBD1Q), a screening question for dream enactment with a simple yes/no response.
Four hundred and eighty-four sleep-clinic-based participants (242 idiopathic RBD patients and 242 controls) completed the screen during a multicenter case-control study. All participants underwent a polysomnogram to define gold-standard diagnosis according to standard criteria.
We found a sensitivity of 93.8% and a specificity of 87.2%. Sensitivity and specificity were similar in healthy volunteers, compared to controls or patients with other sleep diagnoses.
A single-question screen for RBD may reliably detect disease, with psychometric properties favorably comparable to those reported for longer questionnaires.
特发性快速眼动（REM）睡眠行为障碍（RBD）是一种睡眠障碍，是帕金森病（PD）和路易体痴呆的重要危险因素。其患病率尚不清楚。确定患病率的一个障碍是，目前的筛查工具对于大规模的流行病学调查来说太长了。因此，我们设计了 REM 睡眠行为障碍单问题筛查（RBD1Q），这是一个用于梦境行为的筛查问题，答案为简单的“是/否”。
484 名睡眠诊所参与者（242 名特发性 RBD 患者和 242 名对照者）在一项多中心病例对照研究中完成了该筛查。所有参与者都进行了多导睡眠图检查，根据标准标准定义了金标准诊断。
我们发现敏感性为 93.8%，特异性为 87.2%。与对照组或其他睡眠诊断患者相比，健康志愿者的敏感性和特异性相似。
RBD 的单问题筛查可能可靠地检测疾病，其心理测量特性与报告的更长问卷相当。
