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成年人牙齿缺失与血压升高有关——一项多学科的基于人群的研究。

Tooth loss is associated with increased blood pressure in adults--a multidisciplinary population-based study.

机构信息

Oral Epidemiology and Dental Public Health Research Group, Post-Graduate Program in Public Health, Federal University of Santa Catarina, Florianópolis, Brazil.

出版信息

J Clin Periodontol. 2012 Sep;39(9):824-33. doi: 10.1111/j.1600-051X.2012.01916.x. Epub 2012 Jun 26.

Abstract

OBJECTIVES

To investigate whether tooth loss is associated with increased blood pressure among adults after controlling for socioeconomic, health, and lifestyle confounders. We also assessed the interactions between tooth loss and smoking status and tooth loss and age on systolic blood pressure (SBP).

MATERIAL AND METHODS

A population-based cross-sectional study was carried out with 1720 adults from Florianópolis, Brazil. Data collection included blood pressure, anthropometric measures, and a questionnaire on socio-demographics, self-rated health, diabetes, self-reported number of natural teeth, and dental prosthesis. We used linear multivariable regression models for the association of blood pressure with tooth loss adjusting for potential confounders.

RESULTS

Edentulous subjects had a SBP 8.3 mmHg (95% CI 0.1; 16.7) higher than those with more than 10 teeth in both arches after adjustment for potential confounders. We found interaction between tooth loss and smoking status. Moderate/heavy smokers were associated with considerably higher SBP than light, former or non-smokers among edentulous and also partly among dentate with less than 10 teeth in at least one arch, but there was no real association between smoking and SBP among those with 10 or more teeth in both arches.

CONCLUSIONS

Total tooth loss is associated with increased levels of SBP in this adult population.

摘要

目的

在控制社会经济、健康和生活方式等混杂因素后,研究牙齿缺失是否与成年人血压升高有关。我们还评估了牙齿缺失与吸烟状况以及牙齿缺失与年龄对收缩压(SBP)的相互作用。

材料和方法

对巴西弗洛里亚诺波利斯的 1720 名成年人进行了一项基于人群的横断面研究。数据收集包括血压、人体测量指标以及社会人口统计学、自我报告健康状况、糖尿病、自我报告的天然牙齿数量和义齿的问卷。我们使用多变量线性回归模型来调整潜在混杂因素后,评估血压与牙齿缺失的相关性。

结果

在调整了潜在的混杂因素后,无牙受试者的收缩压比至少有 10 颗牙齿的受试者高 8.3 毫米汞柱(95%CI 0.1;16.7)。我们发现牙齿缺失与吸烟状况之间存在交互作用。中度/重度吸烟者的收缩压明显高于无牙且轻度、前吸烟者或非吸烟者,也部分高于至少有一个牙弓中少于 10 颗牙齿的有牙者,但在至少有两个牙弓中都有 10 颗或更多牙齿的人群中,吸烟与 SBP 之间并无实际关联。

结论

在该成年人群中,总牙齿缺失与 SBP 水平升高有关。

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