Mozafari Nia K, Sepehri G, Khatmi H, Shakibaie M R
Department of Otorhinolaryngology, Shafa Hospital, Kerman, Iran.
Iran Red Crescent Med J. 2011 Dec;13(12):891-4. Epub 2011 Dec 1.
Chronic supportive otitis media (CSOM) is one of the commonest illnesses in ENT practice. This study was conducted to find out the various aerobic microorganisms associated with CSOM and their current antimicrobial susceptibility patterns to commonly used antimicrobials.
samples were collected from 117 clinically diagnosed cases of CSOM and processed according to standard protocols.
Out of 117 CSOM cases, 105 (86%) showed positive bacterial culture. The Staphylococcus aureus was the commonest aerobic isolate in CSOM. The sensitivity of Staphylococci spp. to commonly used antimicrobials varied from 27.2% for cefixime to 95.5% for gentamicin and coagulase positive. Pseudomonas isolates showed complete (100%) resistance to amoxicillin/clavulanate (co-amoxiclave), cloxacillin and cefixime, and high sensitivity to ciprofloxacin (95%) and cephalexin (90%).
An appropriate knowledge of antibacterial susceptibility of microorganisms would contribute to a rational antibiotic use and the success of treatment for chronic supportive otitis media.
慢性化脓性中耳炎（CSOM）是耳鼻喉科临床最常见的疾病之一。本研究旨在找出与CSOM相关的各种需氧微生物及其对常用抗菌药物的当前药敏模式。
从117例临床诊断为CSOM的病例中采集样本，并按照标准方案进行处理。
在117例CSOM病例中，105例（86%）细菌培养呈阳性。金黄色葡萄球菌是CSOM中最常见的需氧分离菌。葡萄球菌属对常用抗菌药物的敏感性从头孢克肟的27.2%到庆大霉素的95.5%不等，凝固酶阳性。铜绿假单胞菌分离株对阿莫西林/克拉维酸（复方阿莫西林）、氯唑西林和头孢克肟完全耐药（100%），对环丙沙星（95%）和头孢氨苄（90%）高度敏感。
了解微生物的抗菌药敏情况将有助于合理使用抗生素，提高慢性化脓性中耳炎的治疗成功率。
