Savvidou Christiana, Moreno Rodrigo
Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KY 40202, USA.
Hand Surg. 2012;17(2):167-71. doi: 10.1142/S0218810412500153.
The purpose of this study is to identify a possible correlation between statin administration and incidence of spontaneous distal biceps tendon ruptures. We retrospectively reviewed 104 patients with distal biceps tendon rupture that were treated surgically from 2004 to 2010, 102 males and two females with mean age 47 years (range, 22-78). Patients were divided based on the mechanism of injury and statin administration. After statistical analysis, it was found nearly two times more likely to have spontaneous distal biceps tendon rupture with use of statins. Patients in Group 1 (spontaneous tendon rupture) compared to Group 2 (provoked tendon rupture) were older, had weaker postoperative strength but similar postoperative ROM. Patients taking statins compared to those that were not taking statins were older, had same postoperative strength and similar postoperative ROM. Based on the results of our study we conclude that there is a trend of association of spontaneous distal biceps tendon ruptures with statin administration.
本研究的目的是确定他汀类药物的使用与自发性肱二头肌远端肌腱断裂发生率之间可能存在的相关性。我们回顾性分析了2004年至2010年接受手术治疗的104例肱二头肌远端肌腱断裂患者，其中102例男性，2例女性，平均年龄47岁（范围22 - 78岁）。根据损伤机制和他汀类药物的使用情况对患者进行分组。经过统计分析，发现使用他汀类药物时发生自发性肱二头肌远端肌腱断裂的可能性几乎高出两倍。与第2组（诱发性肌腱断裂）相比，第1组（自发性肌腱断裂）的患者年龄更大，术后力量较弱，但术后活动范围相似。服用他汀类药物的患者与未服用他汀类药物的患者相比，年龄更大，术后力量相同，术后活动范围相似。基于我们的研究结果，我们得出结论，自发性肱二头肌远端肌腱断裂与他汀类药物的使用之间存在关联趋势。
