Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands.
Int J Cardiol. 2013 Jul 15;167(1):11-21. doi: 10.1016/j.ijcard.2012.05.093. Epub 2012 Jun 28.
The traditional metallic stents have significant limitations as they predispose to late thrombosis, may preclude surgical revascularization and distort vessel physiology. Bioresorbable scaffolds (BRSs) are a relatively new technology introduced to overcome these drawbacks. The potential of these devices as well as the reported results from their clinical applications attracted interest and drove research and industry towards the development of new BRSs and the improvement of the existing devices. Thus, over the last years considerable progress has been made and today numerous BRSs are available. The aim of this review article is to highlight the potentialities of these devices, describe the evidence from the recent clinical trials and discuss the advantages, limitations and concerns that were aroused during the first implementation of BRSs in clinical arena.
传统的金属支架存在明显的局限性，因为它们容易导致晚期血栓形成，可能妨碍手术血运重建，并改变血管生理学。生物可吸收支架（BRS）是一种相对较新的技术，旨在克服这些缺点。这些设备的潜力以及它们的临床应用报告结果引起了人们的兴趣，并促使研究和行业开发新的 BRS 并改进现有设备。因此，在过去几年中取得了相当大的进展，如今有许多 BRS 可供选择。本文的目的是强调这些设备的潜力，描述最近临床试验的证据，并讨论在 BRS 首次应用于临床领域期间引起的优点、局限性和关注。
