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社区内育龄期妇女多毛症的流行病学:简化评分系统。

Epidemiology of hirsutism among women of reproductive age in the community: a simplified scoring system.

机构信息

Department of Obstetrics and Gynecology, Reproductive Medical Center, Peking University Third Hospital, Beijing, China.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2012 Aug;163(2):165-9. doi: 10.1016/j.ejogrb.2012.03.023. Epub 2012 Jun 28.

Abstract

OBJECTIVE

The purpose of our research was to generate large sample evidence for the clinical diagnostic criteria of hirsutism and to simplify the modified Ferriman-Galwey (mF-G) scoring system for Asian women.

STUDY DESIGN

This study was a large-scale, cross-sectional epidemiologic investigation conducted in 10 provinces of China. A total of 10,120 reproductive-age women in the community were involved in using the mF-G scoring system to evaluate hirsutism.

RESULTS

Of the participants, 95.5% had an mF-G score <5. The strongest contributors to the nine mF-G positions were upper lip, thighs, and lower abdomen. If the cut-off value was set at 2 for these 3 areas, the area under the ROC curve was 0.987 (95% CI 0.983-0.992), which had a sensitivity of 98.7% and a specificity 91.0%. The percentage of hirsutism (mF-G score >4) and the average mF-G score decreased with advancing age.

CONCLUSIONS

An mF-G scoring >4 can be used to diagnose hirsutism in this population. The results also suggest that hair growth involving the upper lip, thighs, and lower abdomen with scores >2 can be used to diagnose hirsutism in women in the community.

摘要

目的

本研究旨在为多囊卵巢综合征患者的临床诊断标准提供大样本证据,并简化改良 Ferriman-Galwey(mF-G)评分系统在亚洲女性中的应用。

研究设计

这是一项在中国 10 个省份进行的大规模、横断面流行病学调查。共有 10120 名社区育龄妇女参与了 mF-G 评分系统评估多毛症。

结果

在参与者中,95.5%的人 mF-G 评分<5。对 9 个 mF-G 部位评分贡献最大的是上唇、大腿和下腹。如果将这 3 个部位的截断值设定为 2,则 ROC 曲线下面积为 0.987(95%CI 0.983-0.992),具有 98.7%的敏感性和 91.0%的特异性。多毛症(mF-G 评分>4)的比例和平均 mF-G 评分随年龄增长而降低。

结论

mF-G 评分>4 可用于该人群的多毛症诊断。研究结果还表明,上唇、大腿和下腹的毛发评分>2 可用于社区妇女的多毛症诊断。

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