Department of Microbiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
Appl Environ Microbiol. 2012 Sep;78(17):6380-5. doi: 10.1128/AEM.00648-12. Epub 2012 Jun 29.
We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.
我们分离到一株新的裂解性铜绿假单胞菌噬菌体,该噬菌体感染需要 IV 型菌毛。PA1Ø 具有广谱杀菌活性,覆盖革兰氏阳性和革兰氏阴性细菌,并且可以清除生物膜细胞。PA1Ø 可能被开发为治疗铜绿假单胞菌和金黄色葡萄球菌混合生物膜相关感染的药物。