Nakajima Satomi, Ito Masaya, Shirai Akemi, Konishi Takako
Division of Adult Mental Health, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Dialogues Clin Neurosci. 2012 Jun;14(2):210-4. doi: 10.31887/DCNS.2012.14.2/snakajima.
Violent death, such as homicide, accident, and suicide, is sudden, unexpected, and caused by intentional power, The prevalence of complicated grief among those bereaved by violent death is 12.5% to 78.0%. The factors affecting this prevalence rate are considered to be comorbid mental disorders, lack of readiness for the death, difficulty in making sense of the death, high level of negative appraisal about the self and others, and various social stressors. Post-traumatic stress disorder is, in particular, considered to contribute to the development of complicated grief by suppressing function of the medial prefrontal cortex and the anterior cingulate cortex, which works at facilitating the normal mourning process. An understanding of the mechanism and biological basis of complicated grief by violent death will be helpful in developing effective preventive intervention and treatment.
暴力死亡，如凶杀、意外事故和自杀，是突然、意外且由故意的力量导致的。在因暴力死亡而失去亲人的人群中，复杂性哀伤的患病率为12.5%至78.0%。影响这一患病率的因素被认为包括共病精神障碍、对死亡缺乏心理准备、难以理解死亡、对自我和他人的负面评价较高以及各种社会压力源。特别是创伤后应激障碍，被认为通过抑制内侧前额叶皮质和前扣带回皮质的功能，从而影响正常哀伤过程的促进，进而导致复杂性哀伤的发展。了解暴力死亡导致的复杂性哀伤的机制和生物学基础，将有助于制定有效的预防干预措施和治疗方法。
