Mahmodlou Rahim, Mohammadi Payvand, Sepehrvand Nariman
Department of Surgery, Imam Khomeini Training Hospital, Urmia University of Medical Sciences, Urmia, Iran.
ISRN Gastroenterol. 2012;2012:968560. doi: 10.5402/2012/968560. Epub 2012 Jun 12.
Background. Colorectal cancer is the third most prevalent cancer worldwide, which is less common in the Middle East; its prevalence demonstrated to be 7 persons per 100,000 populations in Iran. In this study, we aimed to investigate the clinicopathologic features of CRC patients in West Azerbaijan province of Iran. Methods. In this crosssectional study, 546 patients who underwent surgical procedures with the pathologic diagnosis of colorectal cancer in both academic and private hospitals of Urmia were enrolled. Results. The mean age at diagnosis was 55.2 ± 11.5 years. 23% had an age lower than forty years old. Rectal bleeding (26%), abdominal pain (25%), and large bowel obstruction (23%) were three most common presenting symptoms. 26% of patients presented with acute abdomen. 95% of tumors were adenocarcinoma, 4% were lymphoma, and 1% was other rare tumors. Regarding the stage of cancer according to TNM staging system, 6% of patients were in stage I, followed by 37% in stage II, 33% in stage III, and 24% in stage IV. In 44.5% of patients, the tumor was located in rectum. Conclusion. In west Azerbaijan province of Iran, patients with colorectal cancer present in younger age and more advanced stages in comparison with the developed countries.
背景。结直肠癌是全球第三大常见癌症，在中东地区相对少见；据证实，伊朗每10万人口中的患病率为7人。在本研究中，我们旨在调查伊朗西阿塞拜疆省结直肠癌患者的临床病理特征。方法。在这项横断面研究中，纳入了在乌尔米亚的学术医院和私立医院接受手术且病理诊断为结直肠癌的546例患者。结果。诊断时的平均年龄为55.2±11.5岁。23%的患者年龄低于40岁。直肠出血（26%）、腹痛（25%）和大肠梗阻（23%）是最常见的三种症状。26%的患者表现为急腹症。95%的肿瘤为腺癌，4%为淋巴瘤，1%为其他罕见肿瘤。根据TNM分期系统，6%的患者处于I期，其次是37%处于II期，33%处于III期，24%处于IV期。44.5%的患者肿瘤位于直肠。结论。在伊朗西阿塞拜疆省，与发达国家相比，结直肠癌患者发病年龄较轻且分期较晚。
