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[纤维肌痛综合征的补充和替代疗法。系统评价、荟萃分析与指南]

[Complementary and alternative therapies for fibromyalgia syndrome. Systematic review, meta-analysis and guideline].

作者信息

Langhorst J, Häuser W, Bernardy K, Lucius H, Settan M, Winkelmann A, Musial F

机构信息

Innere Medizin V (Naturheilkunde und Integrative Medizin), Kliniken Essen-Mitte, Am Deimelsberg 34a, 45276, Essen, Deutschland.

出版信息

Schmerz. 2012 Jun;26(3):311-7. doi: 10.1007/s00482-012-1178-9.

DOI:10.1007/s00482-012-1178-9
PMID:22760464
Abstract

BACKGROUND

The scheduled update to the German S3 guidelines on fibromyalgia syndrome (FMS) by the Association of the Scientific Medical Societies ("Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften", AWMF; registration number 041/004) was planned starting in March 2011.

MATERIALS AND METHODS

The development of the guidelines was coordinated by the German Interdisciplinary Association for Pain Therapy ("Deutsche Interdisziplinären Vereinigung für Schmerztherapie", DIVS), 9 scientific medical societies and 2 patient self-help organizations. Eight working groups with a total of 50 members were evenly balanced in terms of gender, medical field, potential conflicts of interest and hierarchical position in the medical and scientific fields. Literature searches were performed using the Medline, PsycInfo, Scopus and Cochrane Library databases (until December 2010). The grading of the strength of the evidence followed the scheme of the Oxford Centre for Evidence-Based Medicine. The recommendations were based on level of evidence, efficacy (meta-analysis of the outcomes pain, sleep, fatigue and health-related quality of life), acceptability (total dropout rate), risks (adverse events) and applicability of treatment modalities in the German health care system. The formulation and grading of recommendations was accomplished using a multi-step, formal consensus process. The guidelines were reviewed by the boards of the participating scientific medical societies.

RESULTS AND CONCLUSION

Meditative movement therapies (qi gong, tai chi, yoga) are strongly recommended. Acupuncture can be considered. Mindfulness-based stress reduction as monotherapy and dance therapy as monotherapy are not recommended. Homeopathy is not recommended. In a minority vote, homeopathy was rated as "can be considered". Nutritional supplements and reiki are not recommended. The English full-text version of this article is available at SpringerLink (under "Supplemental").

摘要

背景

德国科学医学协会联合会(“Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften”,AWMF;注册号041/004)计划于2011年3月开始对德国关于纤维肌痛综合征(FMS)的S3指南进行定期更新。

材料与方法

该指南的制定由德国疼痛治疗跨学科协会(“Deutsche Interdisziplinären Vereinigung für Schmerztherapie”,DIVS)、9个科学医学协会和2个患者自助组织协调。8个工作组共有50名成员,在性别、医学领域、潜在利益冲突以及医学和科学领域的层级地位方面实现了均衡。使用Medline、PsycInfo、Scopus和Cochrane图书馆数据库进行文献检索(截至2010年12月)。证据强度分级遵循牛津循证医学中心的方案。这些建议基于证据水平、疗效(疼痛、睡眠、疲劳和健康相关生活质量结果的荟萃分析)、可接受性(总退出率)、风险(不良事件)以及治疗方式在德国医疗保健系统中的适用性。建议的制定和分级通过多步骤的正式共识过程完成。这些指南由参与的科学医学协会的董事会进行了审查。

结果与结论

强烈推荐冥想运动疗法(气功、太极拳、瑜伽)。可以考虑针灸。不推荐以正念减压疗法作为单一疗法以及舞蹈疗法作为单一疗法。不推荐顺势疗法。在少数投票中,顺势疗法被评为“可以考虑”。不推荐营养补充剂和灵气疗法。本文的英文全文版本可在SpringerLink上获取(在“补充材料”下)。

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