Institute of Health and Society, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne NE2 4AX, UK.
Implement Sci. 2012 Jul 4;7:60. doi: 10.1186/1748-5908-7-60.
Clinical practice guidelines are one of the foundations of efforts to improve health care. In 1999, we authored a paper about methods to develop guidelines. Since it was published, the methods of guideline development have progressed both in terms of methods and necessary procedures and the context for guideline development has changed with the emergence of guideline clearing houses and large scale guideline production organisations (such as the UK National Institute for Health and Clinical Excellence). It therefore seems timely to, in a series of three articles, update and extend our earlier paper. In this first paper we discuss: the target audience(s) for guidelines and their use of guidelines; identifying topics for guidelines; guideline group composition (including consumer involvement) and the processes by which guideline groups function and the important procedural issue of managing conflicts of interest in guideline development.
临床实践指南是改善医疗保健工作的基础之一。1999 年，我们撰写了一篇关于制定指南方法的论文。自发表以来，指南制定方法在方法和必要程序方面都有所发展，指南制定的背景也随着指南清理机构和大规模指南制作组织（如英国国家卫生与临床优化研究所）的出现而发生了变化。因此，我们似乎有必要在一系列三篇文章中更新和扩展我们之前的论文。在这第一篇文章中，我们将讨论：指南的目标受众及其对指南的使用；确定指南主题；指南小组的组成（包括消费者参与）以及指南小组运作的过程，以及管理指南制定过程中的利益冲突这一重要程序问题。
