Escritório Regional de Saúde de Colíder, Secretaria Estadual de Saúde de Mato Grosso, Colider, MT, Brasil.
Rev Soc Bras Med Trop. 2013 Jan-Feb;46(1):30-3. doi: 10.1590/s0037-86822012005000002.
Hantavirus is a genus of ribonucleic acid (RNA) viruses included in the family Bunyaviridae. Hantaviruses are rodent-borne zoonoses that, in the last 18 years, became an emergent public health problem in the Americas, causing a severe cardiopulmonary syndrome. This disease has no specific treatment and has a high case fatality. The transmission of hantavirus to man occurs by inhaling aerosols of rodent excreta. The aim of this study was to determine the prevalence of antibodies to hantavirus in the population of the rural settlement of Tupã in the county of Marcelândia, state of Mato Grosso, Brazil.
The participants of the serologic survey were visited at their homes and selected randomly among the settlement population. Blood samples of the participants were collected by venopuncture. The serum samples were tested by an IgG-ELISA using an N recombinant protein of Araraquara hantavirus as antigen, using the protocol previously established by Figueiredo et al.
IgG antibodies to hantavirus were detected in 7 (13%) of the 54 participants. The positivity was higher among men. It was observed that there was an association of seropositivity to hantavirus within the participants born in the south of Brazil.
The results suggest that, in this rural area, everyone is exposed to the same risk of becoming infected with hantavirus, and, therefore, there is a need to intensify surveillance activities and education of the local people to prevent this viral infection.
汉坦病毒是一种核糖核酸（RNA）病毒，属于布尼亚病毒科。汉坦病毒是一种由啮齿动物传播的人畜共患病，在过去的 18 年中，已成为美洲地区的一个新出现的公共卫生问题，导致严重的心肺综合征。这种疾病没有特定的治疗方法，死亡率很高。汉坦病毒通过吸入啮齿动物排泄物的气溶胶传播给人类。本研究旨在确定巴西马托格罗索州马塞兰迪亚县图帕农村住区居民中汉坦病毒抗体的流行率。
血清学调查的参与者在家中接受访问，并在住区居民中随机选择。通过静脉穿刺采集参与者的血样。使用 Araraquara 汉坦病毒的 N 重组蛋白作为抗原，通过 Figueiredo 等人先前建立的方案，使用 IgG-ELISA 检测血清样本。
在 54 名参与者中，有 7 名（13%）检测到汉坦病毒 IgG 抗体。男性的阳性率较高。观察到在出生于巴西南部的参与者中，汉坦病毒血清阳性存在相关性。
结果表明，在这个农村地区，每个人都面临着相同的感染汉坦病毒的风险，因此需要加强监测活动和对当地居民的教育，以预防这种病毒感染。
