巴西戈亚斯州雅泰市汉坦病毒血清阳性诊断
Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil.
作者信息
Moreli Marcos Lázaro, Novaes Daiane Pereira da Silva, Flor Enia Cristina, Saivish Marielena Vogel, Costa Vivaldo Gomes da
机构信息
Instituto de Ciências da Saúde, Universidade Federal de Goiás, Jataí, GO, Brasil.
Laboratório Elzevir Ferreira Lima, Jataí, GO, Brasil.
出版信息
Rev Soc Bras Med Trop. 2017 Jul-Aug;50(4):530-534. doi: 10.1590/0037-8682-0035-2017.
INTRODUCTION
: Emerging diseases are of great interest, especially those associated with high mortality rates such as hantaviruses. We aimed to conduct a seroepidemiological survey to determine the levels of hantavirus infection.
METHODS
: In-house enzyme-linked immunosorbent assay (ELISA) was used to detect specific antibodies.
RESULTS
: Of the 429 samples collected, seropositivity of 3.9% to anti-hantavirus immunoglobulin G (IgG) was observed (CI 95%: 2.3-5.7). Moreover, in three cases, immunoglobulin M (IgM) was detected, of which two were diagnosed as hantavirus cardiopulmonary syndrome (HCPS).
CONCLUSIONS
: Our data indicate the considerable occurrence of previous hantavirus infections, highlighting occurrences from sub-clinical cases to HCPS.
引言
新发疾病备受关注，尤其是那些与高死亡率相关的疾病，如汉坦病毒。我们旨在开展一项血清流行病学调查，以确定汉坦病毒感染水平。
方法
采用内部酶联免疫吸附测定（ELISA）检测特异性抗体。
结果
在收集的429份样本中，观察到抗汉坦病毒免疫球蛋白G（IgG）血清阳性率为3.9%（95%置信区间：2.3 - 5.7）。此外，在3例样本中检测到免疫球蛋白M（IgM），其中2例被诊断为汉坦病毒心肺综合征（HCPS）。
结论
我们的数据表明既往汉坦病毒感染相当普遍，突出了从亚临床病例到HCPS的发病情况。
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