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Leydig cell function in streptozotocin-induced diabetic rats.

作者信息

Paz G, Homonnai Z T

出版信息

Experientia. 1979 Oct 15;35(10):1412-3. doi: 10.1007/BF01964042.

DOI:10.1007/BF01964042
PMID:227718
Abstract

Streptozotocin diabetic rats were infertile as a result of decreased Leydig cell function of the testes. The major changes found were: decreased number of Leydig cells and their spontaneous secretion of testosterone. No change in the receptors to LH on the Leydig cells was observed. LH was found to be obligatory for the regulation of Leydig cell function and fertility.

摘要

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The effects of alloxan diabetes on the reproductive system of young male rats.四氧嘧啶糖尿病对幼年雄性大鼠生殖系统的影响。
Acta Endocrinol (Copenh). 1961 Nov;38:432-40. doi: 10.1530/acta.0.0380432.
2
Semen quality and certain disturbances of reproduction in diabetic men.
Fertil Steril. 1960 May-Jun;11:255-61. doi: 10.1016/s0015-0282(16)33781-5.
3
DISORDERS OF SEXUAL FUNCTION IN MALE DIABETICS.男性糖尿病患者的性功能障碍
Diabetes. 1963 Nov-Dec;12:519-27. doi: 10.2337/diab.12.6.519.
Front Endocrinol (Lausanne). 2019 Sep 18;10:628. doi: 10.3389/fendo.2019.00628. eCollection 2019.
4
Contemporaneous effects of diabetes mellitus and hypothyroidism on spermatogenesis and immunolocalization of Claudin-11 inside the seminiferous tubules of mice.糖尿病和甲状腺功能减退对小鼠生精作用及生精小管内Claudin-11免疫定位的同期影响。
BMC Dev Biol. 2018 Jun 26;18(1):15. doi: 10.1186/s12861-018-0174-4.
5
Effects of hydro-alcoholic extract of Launaea acanthodes on serum gonadotropin and testosterone levels and the structure of seminiferous tubules in hyperglycemic rats.刺苞菜蓟水醇提取物对高血糖大鼠血清促性腺激素、睾酮水平及生精小管结构的影响
Chin J Integr Med. 2016 Mar;22(3):207-13. doi: 10.1007/s11655-015-2315-y. Epub 2015 Dec 17.
6
Antioxidant treatment with edaravone or taurine ameliorates diabetes-induced testicular dysfunction in the rat.依达拉奉或牛磺酸的抗氧化治疗可改善大鼠糖尿病引起的睾丸功能障碍。
Mol Cell Biochem. 2012 Oct;369(1-2):195-204. doi: 10.1007/s11010-012-1382-z. Epub 2012 Jul 5.
7
Evaluation of chromosomal instability in diabetic rats treated with naringin.评价柚皮苷治疗糖尿病大鼠的染色体不稳定性。
Oxid Med Cell Longev. 2011;2011:365292. doi: 10.1155/2011/365292. Epub 2011 Sep 20.
8
Morphological changes in the hypothalamic-hypophyseal-gonadal axis of male rats after twelve months of streptozotocin-induced diabetes.链脲佐菌素诱导的糖尿病持续十二个月后雄性大鼠下丘脑-垂体-性腺轴的形态学变化
Diabetologia. 1981 Nov;21(5):476-81. doi: 10.1007/BF00257789.
9
Effect of streptozotocin diabetes on adenosine-5'-triphosphate, oxygen consumption and steroidogenesis in testis mitochondria from rats.链脲佐菌素诱导的糖尿病对大鼠睾丸线粒体中三磷酸腺苷、氧消耗及类固醇生成的影响。
Experientia. 1982 Aug 15;38(8):907-8. doi: 10.1007/BF01953646.
4
Studies in human reproduction. II. The influence of diabetes mellitus in men upon reproduction.人类生殖研究。II. 男性糖尿病对生殖的影响。
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5
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6
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Endocrinology. 1972 Aug;91(2):463-9. doi: 10.1210/endo-91-2-463.
7
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8
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Isr J Med Sci. 1978 Oct;14(10):1073-8.
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Testicular lesions of streptozotocin diabetic rats.链脲佐菌素诱导的糖尿病大鼠的睾丸病变
Horm Res. 1975;6(3):138-44. doi: 10.1159/000178671.