McCarthy Cameron G, Alleman Rick J, Bell Zach W, Bloomer Richard J
Cardiorespiratory/Metabolic Laboratory, Department of Health and Sport Sciences, University of Memphis, Memphis, TN, USA.
Integr Med Insights. 2012;7:7-14. doi: 10.4137/IMI.S9720. Epub 2012 Jun 19.
Impaired sleep quality is commonplace within industrialized societies, as evidenced by the increasing number of prescription sleep aids available. Certain herbal preparations have been suggested to provide a natural benefit to sleep; however, limited controlled data are available documenting this benefit. In the present study we tested the effect of an experimental dietary supplement, containing the active ingredients Chlorophytum borivilianum and Velvet bean, on sleep quality using the Pittsburgh Sleep Quality Index (PSQI).
Eighteen healthy and active men and women, with evidence of impaired sleep quality, consumed the supplement daily for 28 days. The PSQI was administered before and after the intervention period. As indicators of safety, resting heart rate and blood pressure were measured, and a complete blood count, comprehensive metabolic panel, and lipid panel were determined.
Sleep quality was influenced by the supplement, as evidenced by an improvement in every category of the PSQI questionnaire (P < 0.05), with most category scores improving approximately 50% from pre to post intervention. No adverse outcomes were noted with use of the supplement, as indicated by no change in resting heart rate, blood pressure, or any bloodborne parameter.
An investigational dietary supplement containing the active ingredients Chlorophytum borivilianum and Velvet bean improves sleep quality in men and women. Additional placebo controlled trials are needed to corroborate these findings in individuals with self-reported sleeping difficulty.
睡眠质量受损在工业化社会中很常见,市面上越来越多的处方助眠药物就证明了这一点。某些草药制剂被认为对睡眠有天然益处;然而,证明这种益处的对照数据有限。在本研究中,我们使用匹兹堡睡眠质量指数(PSQI)测试了一种含有活性成分波棱豆和藜豆的实验性膳食补充剂对睡眠质量的影响。
18名睡眠质量受损的健康活跃男女,每天服用该补充剂,持续28天。在干预期前后进行PSQI评估。作为安全性指标,测量静息心率和血压,并测定全血细胞计数、综合代谢指标和血脂指标。
该补充剂对睡眠质量有影响,PSQI问卷的各个类别均有改善(P < 0.05),大多数类别得分从干预前到干预后提高了约50%。使用该补充剂未观察到不良后果,静息心率、血压或任何血液参数均无变化。
一种含有活性成分波棱豆和藜豆的实验性膳食补充剂可改善男女的睡眠质量。需要更多的安慰剂对照试验来证实这些结果在自述有睡眠困难的个体中的情况。