Salter Shanah, Brownie Sonya
Aust Fam Physician. 2010 Jun;39(6):433-7.
To evaluate the efficacy of valerian and hops in the treatment of primary insomnia.
The AMED and MEDLINE databases were searched for primary sources of literature published between 1950 and 2009, using keywords: herbal medicine, medicinal plants, herbal, Valeriana officinalis, valerian, Humulus lupulus, hops, sleep, insomnia. Studies were included if they evaluated the efficacy of valerian or hops in improving primary insomnia in adults: sixteen studies met the inclusion criteria. Twelve of these found that the use of valerian, on its own, or in combination with hops, is associated with improvements in some sleep parameters (eg. sleep latency and quality of sleep). However, these results need to be interpreted cautiously as there were significant differences in design between the studies.
Further randomised, double blind, placebo controlled trials are needed before such herbal treatments can be confidently recommended for the treatment of primary insomnia.
评估缬草和啤酒花治疗原发性失眠的疗效。
检索AMED和MEDLINE数据库,查找1950年至2009年间发表的文献的主要来源,使用关键词:草药、药用植物、草本、缬草、缬草根、啤酒花、蛇麻草、睡眠、失眠。如果研究评估了缬草或啤酒花改善成人原发性失眠的疗效,则纳入研究:16项研究符合纳入标准。其中12项研究发现,单独使用缬草或与啤酒花联合使用,与某些睡眠参数(如睡眠潜伏期和睡眠质量)的改善有关。然而,由于研究之间的设计存在显著差异,这些结果需要谨慎解释。
在可以放心推荐此类草药治疗原发性失眠之前,需要进一步进行随机、双盲、安慰剂对照试验。