Department of Midwifery, Herbal Research Center, Shahed University, Tehran, Iran.
BMC Complement Altern Med. 2012 Jul 10;12:92. doi: 10.1186/1472-6882-12-92.
Zingiber officinale R. rhizome (ginger) is a popular spice that has traditionally been used to combat the effects of various inflammatory diseases. The aim of this study was to evaluate the effects of ginger on pain relief in primary dysmenorrhea.
This was a randomized, controlled trial. The study was based on a sample of one hundred and twenty students with moderate or severe primary dysmenorrhea. The students were all residents of the dormitories of Shahed University. They were randomly assigned into two equal groups, one for ginger and the other for placebo in two different treatment protocols with monthly intervals. The ginger and placebo groups in both protocols received 500 mg capsules of ginger root powder or placebo three times a day. In the first protocol ginger and placebo were given two days before the onset of the menstrual period and continued through the first three days of the menstrual period. In the second protocol ginger and placebo were given only for the first three days of the menstrual period. Severity of pain was determined by a verbal multidimensional scoring system and a visual analogue scale.
There was no difference in the baseline characteristics of the two groups (placebo n = 46, ginger n = 56). The results of this study showed that there were significant differences in the severity of pain between ginger and placebo groups for protocol one (P = 0.015) and protocol two (P = 0.029). There was also significant difference in duration of pain between the two groups for protocol one (P = 0.017) but not for protocol two (P = 0.210).
Treatment of primary dysmenorrhea in students with ginger for 5 days had a statistically significant effect on relieving intensity and duration of pain.
IRCT201105266206N3.
生姜（姜）是一种常见的香料，传统上被用于缓解各种炎症性疾病的影响。本研究旨在评估生姜对原发性痛经止痛的影响。
这是一项随机对照试验。该研究基于 120 名中度或重度原发性痛经的学生样本。学生均为沙希德大学宿舍的居民。他们被随机分为两组，两组分别在两种不同的治疗方案中以每月间隔服用 500 毫克生姜根粉胶囊或安慰剂，每组 60 人。在第一个方案中，生姜和安慰剂在月经周期开始前两天给予，并持续到月经周期的前三天。在第二个方案中，仅在月经周期的前三天给予生姜和安慰剂。疼痛的严重程度通过口头多维评分系统和视觉模拟评分来确定。
两组的基线特征无差异（安慰剂 n = 46，生姜 n = 56）。本研究结果表明，在方案一（P = 0.015）和方案二（P = 0.029）中，生姜和安慰剂组之间的疼痛严重程度存在显著差异。在方案一（P = 0.017）中，两组之间的疼痛持续时间也存在显著差异，但在方案二（P = 0.210）中则没有。
在学生中用生姜治疗原发性痛经 5 天对缓解疼痛强度和持续时间有统计学意义。
IRCT201105266206N3。
