Generalov S I, Mareeva T E
Akush Ginekol (Mosk). 1990 Sep(9):22-4.
Free radical lipid oxidation and activity of lysosomal enzymes have been tested in 87 pregnant women with acquired and congenital heart diseases and pulmonary circulatory failure. Activation of lipid peroxidation directly correlated with the severity of circulatory failure. These processes aggravated maternal and fetal hypoxia. A management protocol was designed and tried using medical and nonmedical methods. Its use was associated with an appreciable reduction in perinatal morbidity and mortality rates in this pool of pregnancies.
对87例患有后天性和先天性心脏病及肺循环衰竭的孕妇进行了自由基脂质氧化和溶酶体酶活性检测。脂质过氧化的激活与循环衰竭的严重程度直接相关。这些过程加重了母婴缺氧。设计并尝试了一种使用医学和非医学方法的管理方案。在这组妊娠中，该方案的使用与围产期发病率和死亡率的显著降低相关。
