急性汉坦病毒感染中针对多种细菌和病毒病原体的免疫球蛋白M抗体的出现情况。
Occurrence of immunoglobulin M antibodies against several bacterial and viral pathogens in acute hantavirus infection.
作者信息
Wellinghausen Nele, Goetz Andrea, Weber Ursula
机构信息
Dr. Gaertner and Colleagues Laboratory, Ravensburg, Germany.
出版信息
Clin Vaccine Immunol. 2012 Sep;19(9):1549-51. doi: 10.1128/CVI.00109-12. Epub 2012 Jul 11.
Abstract
Elevated levels of immunoglobulin M antibodies against various pathogens, most frequently Epstein-Barr-virus and Coxiella burnetii, were detected by immunoassay in 15 of 48 patients (31.3%) with acute Puumala virus infections. Although the mechanisms leading to this IgM response are not clear yet, polyspecific immunoglobulin M antibodies have to be taken into account to avoid misinterpretation of serological results in acute hantavirus infection.
摘要
通过免疫测定法在48例急性普马拉病毒感染患者中的15例（31.3%）检测到针对多种病原体的免疫球蛋白M抗体水平升高，其中最常见的是爱泼斯坦-巴尔病毒和伯纳特立克次体。虽然导致这种IgM反应的机制尚不清楚，但在急性汉坦病毒感染中，必须考虑多特异性免疫球蛋白M抗体，以避免血清学结果的误判。
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