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GabiPD - 初级 GABI 数据库整合了植物蛋白质组学数据和以基因为中心的信息。

GabiPD - The GABI Primary Database integrates plant proteomic data with gene-centric information.

机构信息

Max Planck Institute of Molecular Plant Physiology, Potsdam, Germany.

出版信息

Front Plant Sci. 2012 Jul 9;3:154. doi: 10.3389/fpls.2012.00154. eCollection 2012.

DOI:10.3389/fpls.2012.00154
PMID:22787465
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3391694/
Abstract

GabiPD is an integrative plant "omics" database that has been established as part of the German initiative for Genome Analysis of the Plant Biological System (GABI). Data from different "omics" disciplines are integrated and interactively visualized. Proteomics is represented by data and tools aiding studies on the identification of post-translational modification and function of proteins. Annotated 2D electrophoresis-gel images are offered to inspect protein sets expressed in different tissues of Arabidopsis thaliana and Brassica napus. From a given protein spot, a link will direct the user to the related GreenCard Gene entry where detailed gene-centric information will support the functional annotation. Beside MapMan- and GO-classification, information on conserved protein domains and on orthologs is integrated in this GreenCard service. Moreover, all other GabiPD data related to the gene, including transcriptomic data, as well as gene-specific links to external resources are provided. Researches interested in plant protein phosphorylation will find information on potential MAP kinase substrates identified in different protein microarray studies integrated in GabiPD's Phosphoproteomics page. These data can be easily compared to experimentally identified or predicted phosphorylation sites in PhosPhAt via the related Gene GreenCard. This will allow the selection of interesting candidates for further experimental validation of their phosphorylation.

摘要

GabiPD 是一个综合性的植物“组学”数据库,它是德国植物生物系统基因组分析计划(GABI)的一部分。不同“组学”学科的数据被整合并进行交互式可视化。蛋白质组学由辅助研究蛋白质翻译后修饰和功能的工具和数据表示。提供经过注释的二维电泳凝胶图像,以检查拟南芥和油菜不同组织中表达的蛋白质组。从给定的蛋白质斑点,用户可以链接到相关的 GreenCard 基因条目,其中详细的基因中心信息将支持功能注释。除了 MapMan 和 GO 分类,还整合了保守蛋白质结构域和同源物的信息。此外,还提供了与该基因相关的所有其他 GabiPD 数据,包括转录组数据,以及特定于基因的外部资源链接。对植物蛋白磷酸化感兴趣的研究人员可以在 GabiPD 的磷酸化蛋白质组学页面中找到整合的不同蛋白质微阵列研究中鉴定的潜在 MAP 激酶底物的信息。这些数据可以通过相关的基因 GreenCard 与 PhosPhAt 中实验鉴定或预测的磷酸化位点进行轻松比较。这将允许选择有趣的候选者,以进一步实验验证其磷酸化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ea/3391694/d95cea36e337/fpls-03-00154-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ea/3391694/8539998eb974/fpls-03-00154-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ea/3391694/d95cea36e337/fpls-03-00154-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ea/3391694/8539998eb974/fpls-03-00154-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97ea/3391694/d95cea36e337/fpls-03-00154-g002.jpg

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The green proteome: challenges in plant proteomics.绿色蛋白质组:植物蛋白质组学面临的挑战
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