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猫环层小体的免疫组织化学研究:波形蛋白和S-100蛋白样物质在核心内部的共定位。

Immunohistochemical study of cat Pacinian corpuscles: co-localization of vimentin- and S-100 protein-like in the inner core.

作者信息

Vega J A, Zubizarreta J J, del Valle M E, Hernández L C, Bengoechea M E, Pérez-Casas A

机构信息

Departamento de Morfología y Biología Celular, Universidad de Oviedo, Spain.

出版信息

Cell Mol Biol. 1990;36(4):415-20.

PMID:2279265
Abstract

The presence of vimentin and S-100 protein in cat Pacinian corpuscles of cat mesentery has been investigated immunohistochemically (streptavidin-biotin method) using monoclonal antibodies. A positive reaction for both vimentin- and S-100 protein-like was found only in the lamellae of the inner core. The presence of vimentin and the co-expression of vimentin/S-100 protein-like in sensory corpuscles is reported for the first time. The authors discuss the origin of the inner core and capsule of sensory corpuscles on the basis of their immunohistochemical characteristics.

摘要

利用单克隆抗体,采用免疫组织化学方法(链霉亲和素-生物素法)研究了猫肠系膜中帕氏小体波形蛋白和S-100蛋白的存在情况。仅在内核的薄片中发现波形蛋白样和S-100蛋白样均呈阳性反应。首次报道了感觉小体中波形蛋白的存在以及波形蛋白/S-100蛋白样的共表达情况。作者根据其免疫组织化学特征讨论了感觉小体内核和被膜的起源。

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