Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada.
J Vasc Surg. 2012 Sep;56(3):656-60. doi: 10.1016/j.jvs.2012.02.027. Epub 2012 Jul 12.
Blunt abdominal aortic injury (BAAI) is very rare, and current literature is limited to case series of single-center experience. Through an analysis of the National Trauma Data Bank, the largest aggregation of United States trauma registry data, our aim was to characterize the associated injury pattern, contemporary management, and in-hospital outcomes of patients with BAAI.
We used a nested case-control design. The overall cohort consisted of adult patients (age ≥ 16 years) severely injured (Injury Severity Score ≥ 16) after blunt trauma who were treated at a level 1 or 2 trauma center in years 2007 to 2009. Cases were patients with BAAI and were frequency-matched by age group and mechanism to randomly selected controls at a one-to-five ratio. Multivariable matched analysis (conditional logistic regression) was used to derive adjusted measures of association between BAAI and adjacent arterial, intra-abdominal, and bony injuries.
We identified 436 patients with BAAI from 180 centers. The mean Injury Severity Score was 35 ± 14, and most patients were injured in motor vehicle crashes (84%). Multivariable analysis showed injury to the thoracic aorta, renal and iliac artery, small bowel, colon, liver, pancreas, and kidney, as well as lumbar spine fractures were independently associated with BAAI. A total of 394 patients (90%) were managed nonoperatively, and 42 (10%) underwent repair. Of these 42 patients, 29 (69%) underwent endovascular repair, with 11 patients undergoing open aortic repair and two extra-anatomic bypasses. Median time from admission to repair was 1 day (interquartile range, 1-2 days). Overall mortality was 29%. A total of 271 (69%) patients managed nonoperatively survived to hospital discharge.
The index of suspicion for BAAI should be raised in severely injured patients by the presence of injuries to the lumbar spine, bowel, retroperitoneal organs, and adjacent major arteries. Although endovascular repair is the most common intervention, most patients are managed nonoperatively and survive to hospital discharge.
钝性腹主动脉损伤(BAAI)非常罕见,目前的文献仅限于单中心经验的病例系列。通过对美国最大的创伤登记数据聚合体——国家创伤数据库进行分析,我们旨在描述 BAAI 患者的相关损伤模式、当代治疗方法和院内结局。
我们采用了嵌套病例对照设计。总体队列包括 2007 年至 2009 年在 1 级或 2 级创伤中心接受治疗的、严重钝性创伤后(损伤严重程度评分≥16 分)的成年患者(年龄≥16 岁)。病例为 BAAI 患者,按年龄组和机制与随机选择的对照组进行频数匹配,比例为 1:5。采用多变量匹配分析(条件逻辑回归)得出 BAAI 与相邻动脉、腹腔内和骨损伤之间的关联调整测量值。
我们从 180 个中心中确定了 436 例 BAAI 患者。平均损伤严重程度评分为 35±14,大多数患者因机动车事故受伤(84%)。多变量分析显示,胸主动脉、肾和髂动脉、小肠、结肠、肝、胰腺和肾脏以及腰椎骨折与 BAAI 独立相关。共有 394 例(90%)患者接受非手术治疗,42 例(10%)患者接受修复。其中 42 例患者中,29 例(69%)接受了血管内修复,11 例接受了开放主动脉修复,2 例接受了体外旁路手术。从入院到修复的中位时间为 1 天(四分位距,1-2 天)。总体死亡率为 29%。共有 271 例(69%)非手术治疗患者存活至出院。
在严重受伤的患者中,存在腰椎、肠道、腹膜后器官和相邻大血管损伤时,应提高对 BAAI 的怀疑指数。尽管血管内修复是最常见的干预措施,但大多数患者接受非手术治疗并存活至出院。