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牛血清白蛋白稳定的胶体银纳米粒子的抗菌性能研究。

Studies on the antimicrobial properties of colloidal silver nanoparticles stabilized by bovine serum albumin.

机构信息

Research and Post Graduate Department of Chemistry, St. Thomas College, Palai, Mahatma Gandhi University, Kottayam, Kerala 686574, India.

出版信息

Colloids Surf B Biointerfaces. 2013 Jan 1;101:14-8. doi: 10.1016/j.colsurfb.2012.05.017. Epub 2012 May 29.

DOI:10.1016/j.colsurfb.2012.05.017
PMID:22796767
Abstract

Colloidal silver nanoparticles were synthesised using sol-gel method and these nanoparticles were stabilised by encapsulated into the scaffolds of bovine serum albumin. Silver nanoparticles and encapsulated products were characterised by FTIR, NMR, XRD, TG, SEM and TEM analyses. Silver nanoparticle encapsulated bovine serum albumin showed highly potent antibacterial activity towards the bacterial strains such as Staphylococcus aureus, Serratia marcescens, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae.

摘要

胶体银纳米粒子是采用溶胶-凝胶法合成的，这些纳米粒子通过包埋在牛血清白蛋白的支架中得到稳定。采用傅里叶变换红外光谱（FTIR）、核磁共振（NMR）、X 射线衍射（XRD）、热重分析（TG）、扫描电子显微镜（SEM）和透射电子显微镜（TEM）对银纳米粒子和包埋产物进行了表征。银纳米粒子包埋牛血清白蛋白对金黄色葡萄球菌、粘质沙雷氏菌、铜绿假单胞菌、大肠杆菌和肺炎克雷伯菌等细菌菌株表现出很强的抗菌活性。

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