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胶态银纳米粒子/鼠李糖脂(SNPRL)复合物作为新型趋化抗菌剂。

Colloidal silver nanoparticles/rhamnolipid (SNPRL) composite as novel chemotactic antibacterial agent.

机构信息

Department of Molecular Biology and Biotechnology, Tezpur (Central) University, Napaam, Tezpur 784028, Assam, India.

出版信息

Int J Biol Macromol. 2013 Oct;61:238-42. doi: 10.1016/j.ijbiomac.2013.07.006. Epub 2013 Jul 12.

DOI:10.1016/j.ijbiomac.2013.07.006
PMID:23850558
Abstract

The antibacterial activity of silver nanoparticles and rhamnolipid are well known individually. In the present research, antibacterial and chemotactic activity due to colloidal silver nanoparticles (SNP), rhamnolipid (RL) and silver nanoparticles/rhamnolipid composite (SNPRL) were evaluated using Staphylococcus aureus (MTCC3160), Escherichia coli (MTCC40), Pseudomonas aeruginosa (MTCC8163) and Bacillus subtilis (MTCC441) as test strains. Further, the SNPRL nanoparticles were characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR). The observation clearly indicates that SNPRL shows prominent antibacterial and chemotactic activity in comparison to all of its individual precursor components.

摘要

银纳米粒子和鼠李糖脂的抗菌活性是众所周知的。在本研究中,使用金黄色葡萄球菌(MTCC3160)、大肠杆菌(MTCC40)、铜绿假单胞菌(MTCC8163)和枯草芽孢杆菌(MTCC441)作为测试菌株,评估了胶体银纳米粒子(SNP)、鼠李糖脂(RL)和银纳米粒子/鼠李糖脂复合物(SNPRL)的抗菌和趋化活性。此外,使用扫描电子显微镜(SEM)、透射电子显微镜(TEM)和傅里叶变换红外光谱(FTIR)对 SNPRL 纳米粒子进行了表征。观察结果清楚地表明,与所有单一的前体成分相比,SNPRL 表现出显著的抗菌和趋化活性。

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